Best-value alternatives
Alternatives to Layla
Layla scores 59/100 on our Cost-Efficiency Index (ranked #274 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.
- Our #1 pick01A94/ 100Index
CoreAge Rx
Ranked #1Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
- 02C59/ 100Index
June Health
Ranked #273June Health (tryjunehealth.com) is a newly-registered (~May 2026) compounded-GLP-1 telehealth storefront advertising 'Medical Weight Loss from $199/mo' without breaking pricing out by drug, naming a medical director.
- Sema
- $199/mo (compounded)
- Tirz
- $199/mo (compounded)
- Coverage
- Multi-state
- Brand
- Compounded
- 03C59/ 100Index
Invyncible
Ranked #272Invyncible (operated by Nationwide Telemedicine, LLC, St. Petersburg, FL) sells four semaglutide combo programs ($149-$270) and four tirzepatide combo programs ($180-$318.75), plus an oral semaglutide capsule program at $255.50, across 46 states and DC.
- Sema
- $149/mo (0.45 mg dose, compounded with glycine + B12)
- Tirz
- $180/mo (2.5 mg weekly, 4-week program, compounded)
- Coverage
- 46 states plus DC
- Brand
- Yes
- 04C59/ 100Index
CLYR Health
Ranked #271CLYR Health (clyr.health, not to be confused with the unrelated clyrhealth.com skincare brand) is a telehealth GLP-1 provider using MD Integrations, PC as its prescribing medical group and a 503A compounding pharmacy.
- Sema
- $169/mo (compounded)
- Tirz
- $199/mo (compounded)
- Coverage
- Multi-state
- Brand
- Yes
- 05C59/ 100Index
Carocare Wellness
Ranked #270Carocare Wellness is a Houston-based medical weight-loss clinic offering compounded semaglutide and tirzepatide on a dose-escalating monthly ladder, with 3-month bundle discounts.
- Sema
- $150/mo (0.25 mg dose, compounded)
- Tirz
- $200/mo (2.5 mg dose, compounded)
- Coverage
- 1 state
- Brand
- Yes
- 06C59/ 100Index
Boston Medical Group
Ranked #269Boston Medical Group is an established medical group running a 12-week compounded GLP-1 weight-loss program.
- Sema
- $199/mo (starting strength, rising with dose, compounded)
- Tirz
- Not disclosed
- Coverage
- 7 states
- Brand
- Compounded
- 07C59/ 100Index
Belle Health
Ranked #268Belle Health (joinbelle.com) is a DTC telehealth platform selling compounded semaglutide and tirzepatide at flat rates that don't increase with dose, sourced from a panel of named compounding pharmacies rather than one exclusive partner.
- Sema
- Not disclosed
- Tirz
- Not disclosed
- Coverage
- All 50 states
- Brand
- Compounded
Regulatory note: the FDA issued a warning letter to Belle Health LLC dba Belle in February 2026. We still list and link to Belle Health; you should know the letter is on the public record before you decide.
- 08C59/ 100Index
AVArx
Ranked #267AVArx (real domain getavarx.com -- avarx.com is parked/for sale) is a Glendale.
- Sema
- $199/mo (compounded)
- Tirz
- $199/mo (compounded)
- Coverage
- All 50 states
- Brand
- Compounded
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.