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Head-to-head · Cost-Efficiency Index

Harmony Wellness Clinic vs MediRX

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #338

Harmony Wellness Clinic

Patients who want to see the full dose-tiered price range upfront rather than a single 'starting at' teaser.

Visit Harmony Wellness Clinic
VS
Grade C · #339

MediRX

Shoppers who want transparent published pricing and don't mind that prescribing is handled by a third-party clinician network (OpenLoop) rather than an in-house medical team.

Visit MediRX

The verdict

Too close to callGrade C vs C

Harmony Wellness Clinic and MediRX tie on the Cost-Efficiency Index at 55/100, so neither wins outright on the numbers. For most shoppers we'd start with Harmony Wellness Clinic (ranked #338, a hair above #339) — Patients who want to see the full dose-tiered price range upfront rather than a single 'starting at' teaser. But MediRX is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Harmony Wellness Clinic.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

48
58

Price Transparency

30
78

Nationwide Access

66
24

Formulation Options

66
66

Clinical Oversight

78
74

Contract Flexibility

55
20

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecHarmony Wellness ClinicMediRX
Cost-Efficiency Index55/10055/100
Semaglutide / mo$200/mo (compounded)$149/mo (starting dose, compounded)
Tirzepatide / mo$250/mo (compounded)$199/mo (starting dose, compounded)
Semaglutide / yr (modeled)$2,400$1,788
Tirzepatide / yr (modeled)$3,000$2,388
Coverage36 statesCoverage not published
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank here#338#339

Harmony Wellness Clinic

55/100

Where the value is

  • Named nurse-practitioner founder/clinical lead with disclosed credentials and experience
  • Transparent full-range tiered pricing shown directly on the services page
  • Broad stated footprint: telehealth network across 40+ states

The tradeoffs

  • A LegitScript certification claimed by a third-party review site could NOT be independently verified
  • No compounding pharmacy partner named
Visit Harmony Wellness Clinic

Full Harmony Wellness Clinic review →

MediRX

55/100

Where the value is

  • Publishes specific dollar pricing for both injection and oral-tablet forms of both drugs
  • Rare self-disclosed distinction between promotional ($149) and standard ($179) semaglutide pricing
  • LegitScript badge displayed on the page

The tradeoffs

  • MediRx itself has no named medical director -- all clinical care is outsourced to OpenLoop Health's network
  • Tirzepatide's wide $199-$399 range makes the true likely monthly cost at a therapeutic dose unclear
Visit MediRX

Full MediRX review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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