Head-to-head · Cost-Efficiency Index
FMmeds vs Rx.com
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
FMmeds
Cost-first shoppers who want a genuinely all-in flat monthly price that doesn't rise as your dose increases.
Visit FMmedsRx.com
Someone who will judge it by the plan card rather than the banner, and who values no auto-renewal and a named pharmacy over the lowest sticker.
Visit Rx.comThe verdict
FMmeds takes it, leading the Cost-Efficiency Index 78 to 77. FMmeds is a compounded-GLP-1 telehealth membership selling semaglutide from $95/mo and tirzepatide from $145/mo, both co-formulated with Vitamin B12 and dispensed by Manifest Pharmacy. Rx.com still earns a C — Someone who will judge it by the plan card rather than the banner, and who values no auto-renewal and a named pharmacy over the lowest sticker.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs FMmeds.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | FMmeds | Rx.com |
|---|---|---|
| Cost-Efficiency Index | 78/100 | 77/100 |
| Semaglutide / mo | $95/mo (all doses, plus a separate fee, compounded) | $175/mo month-to-month; $165 on three months and $146 on six |
| Tirzepatide / mo | $145/mo (all doses, plus a separate fee, compounded) | $285/mo month-to-month; $265 on three months and $259 on six |
| Semaglutide / yr (modeled) | $1,140 | $2,100 |
| Tirzepatide / yr (modeled) | $1,740 | $3,420 |
| Coverage | All 50 states | 49 states on its plan page; its own banner says all 50 |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #41 | #45 |
FMmeds
78/100Where the value is
- The advertised price is confirmed all-in on the site's own FAQ (visit, physician review, and medication), not a bare medication cost
- Explicitly flat regardless of dose escalation — a real, published guarantee, not just a claim
- Named 503A compounding pharmacy (Manifest Pharmacy) and a real support phone/email
The tradeoffs
- Compounded only — not FDA-approved, and the site carries the standard compounded-medication disclaimer
- No states-served list, LegitScript badge, or named prescriber/medical director found on the pages read this session
Rx.com
77/100Where the value is
- "No automatic renewals" is printed under the plan card itself rather than buried in the terms
- Names Manifest Pharmacy in Greer, South Carolina with a full street address, and MD Integrations as the provider network, on the same page as the price
- One flat price at every dose from 2.5 mg to 15 mg, with the provider visit, injection supplies and cold shipping stated as included
The tradeoffs
- The advertised "$146/mo FOR LIFE" is a six-month prepay on semaglutide; month-to-month tirzepatide is $285
- The plan page says 49 states served while the banner on the same site says all 50
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.