Head-to-head · Cost-Efficiency Index
Fierce Health vs Superpower
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Fierce Health
Shoppers specifically seeking a below-standard 'microdose' GLP-1 protocol at a discounted entry price.
Visit Fierce HealthSuperpower
People who want twice-yearly blood work and a GLP-1 prescription on one account, and who will pay a yearly membership to get both.
Visit SuperpowerThe verdict
Fierce Health and Superpower tie on the Cost-Efficiency Index at 55/100, so neither wins outright on the numbers, so choose on fit. Fierce Health: Shoppers specifically seeking a below-standard 'microdose' GLP-1 protocol at a discounted entry price. Superpower: People who want twice-yearly blood work and a GLP-1 prescription on one account, and who will pay a yearly membership to get both.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Fierce Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Fierce Health | Superpower |
|---|---|---|
| Cost-Efficiency Index | 55/100 | 55/100 |
| Semaglutide / mo | Not disclosed | $229/moCompounded, members only; the membership is billed separately |
| Tirzepatide / mo | Not disclosed | Not disclosed |
| Semaglutide / yr (modeled) | — | $2,748 |
| Tirzepatide / yr (modeled) | — | — |
| Coverage | 30 states | Not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #401 | #402 |
Fierce Health
55/100Where the value is
- Semaglutide is currently listed at a steep markdown ($197 vs. a stated $591 regular price) if the discount holds at checkout
- Sells both semaglutide and tirzepatide with clearly separated pricing rather than bundling them
- Discloses the standard compounding/FDA disclaimer plainly in the footer
The tradeoffs
- The $591 'regular price' next to a $197 'sale price' is a large, unexplained gap — no page discloses how long the discount lasts or what the price reverts to
- Neither 'microdose' product states its mg dose
Superpower
55/100Where the value is
- The semaglutide price, $229 a month, is printed on its product page before you sign up
- The membership includes 150+ lab tests across two blood draws a year, at a Quest location or at home
- A licensed physician on its clinical team reviews your questionnaire, and the plan includes weekly check-ins and dose adjustments
The tradeoffs
- Semaglutide is sold to members only, so the $349 yearly membership sits on top of the $229 monthly medication price
- The site prints two membership prices: $349 a year on the homepage and "$17 per month, billed annually" on the semaglutide page
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.