Head-to-head · Cost-Efficiency Index
Fierce Health vs Medi-Weightloss
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Fierce Health
Shoppers specifically seeking a below-standard 'microdose' GLP-1 protocol at a discounted entry price.
Visit Fierce HealthMedi-Weightloss
Shoppers near one of Medi-Weightloss's 130+ US clinics who want in-person labs and are comfortable with location-dependent pricing.
Visit Medi-WeightlossThe verdict
Fierce Health takes it, leading the Cost-Efficiency Index 55 to 54. Fierce Health is a Shopify-storefront telehealth/e-commerce hybrid selling 'microdose' compounded semaglutide (From $197, discounted from a stated $591 regular price) and tirzepatide (From $297, not discounted). Medi-Weightloss still earns a C — Shoppers near one of Medi-Weightloss's 130+ US clinics who want in-person labs and are comfortable with location-dependent pricing.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Fierce Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Fierce Health | Medi-Weightloss |
|---|---|---|
| Cost-Efficiency Index | 55/100 | 54/100 |
| Semaglutide / mo | Not disclosed | $99/mo (starting dose, first-month rate, plus a separate fee, compounded) |
| Tirzepatide / mo | Not disclosed | $199/mo (starting dose, first-month rate, plus a separate fee, compounded) |
| Semaglutide / yr (modeled) | — | $1,188 |
| Tirzepatide / yr (modeled) | — | $2,388 |
| Coverage | 30 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #351 | #358 |
Fierce Health
55/100Where the value is
- Semaglutide is currently listed at a steep markdown ($197 vs. a stated $591 regular price) if the discount holds at checkout
- Sells both semaglutide and tirzepatide with clearly separated pricing rather than bundling them
- Discloses the standard compounding/FDA disclaimer plainly in the footer
The tradeoffs
- The $591 'regular price' next to a $197 'sale price' is a large, unexplained gap — no page discloses how long the discount lasts or what the price reverts to
- No mg dose amount is disclosed for either 'microdose' product on any page reached
Medi-Weightloss
54/100Where the value is
- Over 130 in-person clinic locations across the US with on-site labs and body composition analysis at the new-patient visit
- Publishes real introductory numbers ($99 semaglutide / $199 tirzepatide first month) rather than staying fully opaque
- Insurance path available for branded Zepbound/Wegovy/Saxenda, with the site claiming most insured patients 'pay between $0 and $50 per visit'
The tradeoffs
- The $99/$199 headline figures are explicitly FIRST-MONTH-ONLY; the ongoing self-pay rate 'varies by program and location' and is never published anywhere on the site
- A separate $199 new-patient visit fee is charged before the first month's medication price even applies
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.