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Head-to-head · Cost-Efficiency Index

EverSlim vs Synergy Rx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #48

EverSlim

Cost-first shoppers who want flat-price compounded glp-1 care shipped nationwide.

Visit EverSlim
VS
Grade C · #53

Synergy Rx

People who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by inquiry.

Visit Synergy Rx

The verdict

Winner · EverSlimGrade C vs C

EverSlim takes it, leading the Cost-Efficiency Index 76 to 72. EverSlim is a US telehealth program selling doctor-prescribed compounded GLP-1 medication delivered to the door, with compounded semaglutide from $117 a month and compounded tirzepatide from $140 a month. Synergy Rx still earns a CPeople who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by inquiry.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs EverSlim.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

75
70

Price Transparency

84
65

Nationwide Access

86
62

Formulation Options

66
84

Clinical Oversight

81
90

Contract Flexibility

55
68

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecEverSlimSynergy Rx
Cost-Efficiency Index76/10072/100
Semaglutide / mo$117/mo (compounded)From $199/mo
Tirzepatide / mo$140/mo (compounded)From $349/mo
Semaglutide / yr (modeled)$1,404$2,388
Tirzepatide / yr (modeled)$1,680$4,188
CoverageAll 50 statesNot disclosed
Oral / sublingualNoNo
Brand-name accessCompounded onlyYes
Rank here#48#53

EverSlim

76/100

Where the value is

  • Transparent flat pricing from 127 dollars a month for compounded semaglutide; medication, provider visit, and shipping included with no insurance.
  • Names its pharmacy partners (EPIQ Scripts, Foothills, Emerald) and DrTelx medical group; LegitScript-approved and NABP-accredited.
  • Available in all 50 states and DC, with asynchronous care in 44 states and live-visit access in the rest.

The tradeoffs

  • No price tiers are published anywhere: /pricing is a 404, the footer pricing link is a same-page anchor, and the checkout is behind a login, so what a titrated dose costs is unknowable before signing up
  • Cancellation requires at least 72 hours' notice before the next billing date, or the subscription renews for another cycle
Visit EverSlim

Full EverSlim review →

Synergy Rx

72/100

Where the value is

  • Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate, not compounded only
  • Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
  • A $100 welcome credit applied at checkout, and FSA/HSA eligible

The tradeoffs

  • Prices are published as bare “Starting at” figures with no billing cycle or term attached, so a full-year cost still cannot be modeled before an inquiry
  • At $349/mo tirzepatide sits roughly $100 above the compounded median we track
Visit Synergy Rx

Full Synergy Rx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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