Head-to-head · Cost-Efficiency Index
DoctorAdam vs Jyra Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
DoctorAdam
Shoppers who want a needle-free oral GLP-1 with named prescribers, in the 47 states DoctorAdam actually serves.
Visit DoctorAdamJyra Health
Cost-first shoppers who want low compounded GLP-1 pricing if you're comfortable prepaying a 3-month plan.
Visit Jyra HealthThe verdict
DoctorAdam and Jyra Health tie on the Cost-Efficiency Index at 74/100, so neither wins outright on the numbers. For most shoppers we'd start with DoctorAdam (ranked #58, a hair above #59) — Shoppers who want a needle-free oral GLP-1 with named prescribers, in the 47 states DoctorAdam actually serves. But Jyra Health is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs DoctorAdam.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | DoctorAdam | Jyra Health |
|---|---|---|
| Cost-Efficiency Index | 74/100 | 74/100 |
| Semaglutide / mo | $129/mo (starting dose, compounded oral) | $175/mo (all doses, compounded) |
| Tirzepatide / mo | $199/mo (starting dose, compounded oral) | $199/mo (all doses, compounded) |
| Semaglutide / yr (modeled) | $1,548 | $2,100 |
| Tirzepatide / yr (modeled) | $2,388 | $2,388 |
| Coverage | 44 states | All 50 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #58 | #59 |
DoctorAdam
74/100Where the value is
- Names six actual prescribers with credentials — unusually transparent for a Shopify-based storefront
- Needle-free oral tablet option for both semaglutide (from $129) and tirzepatide (from $199)
- Flat 'no hidden fees' pricing framing, with free 2-3 business day shipping
The tradeoffs
- The homepage claims 'Delivery Across All 50 States' but the site's own FAQ state list is 47 states plus DC — New Jersey, Mississippi, and Alaska are excluded
- Injectable dose-tier pricing could not be verified live in this pass (repeated 429 errors on the product pages); only the oral 'from' price is confirmed
Jyra Health
74/100Where the value is
- Genuine, math-consistent 3-month prepay discount ($111 off semaglutide, $60 off tirzepatide across 3 months) rather than a vague 'up to X% off' claim
- Flat price at every dose with no renewal increase, on both the 1-month and 3-month tiers
- Claims all-50-state coverage with no membership fees and free express delivery
The tradeoffs
- The lower headline-friendly prices ($139/mo semaglutide, $179/mo tirzepatide) are only available by prepaying a full 3-month plan up front, not as a standing month-to-month rate
- No compounding pharmacy is named anywhere on the site
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.