Best-value alternatives
Alternatives to Jyra Health
Jyra Health scores 74/100 on our Cost-Efficiency Index (ranked #59 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.
- Our #1 pick01A94/ 100Index
CoreAge Rx
Ranked #1Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
- 02C74/ 100Index
DoctorAdam
Ranked #58DoctorAdam is a Shopify-storefront telehealth company selling compounded oral (sublingual) and injectable semaglutide and tirzepatide plus NAD+/glutathione add-ons, prescribed by a named roster of six MD/NP prescribers.
- Sema
- $129/mo (starting dose, compounded oral)
- Tirz
- $199/mo (starting dose, compounded oral)
- Coverage
- 44 states
- Brand
- Compounded
- 03C74/ 100Index
Aspen
Ranked #57Aspen Health (startaspen.com) is a cash-pay telehealth platform spanning weight loss, hair health, longevity, and sexual wellness.
- Sema
- $179/mo (all doses, compounded)
- Tirz
- $179/mo (all doses, compounded)
- Coverage
- All 50 states
- Brand
- Compounded
- 04C74/ 100Index
Amble
Ranked #56Amble is a managed-services telehealth platform (by its own terms, not itself a medical facility or pharmacy) selling compounded semaglutide and tirzepatide at IDENTICAL prices on a commitment-length pricing table: $179/mo with no commitment.
- Sema
- $179/mo (all doses, compounded)
- Tirz
- $179/mo (all doses, compounded)
- Coverage
- All 50 states
- Brand
- Compounded
- 05C74/ 100Index
EdgeRx
Ranked #55The best clinical documentation of any newly added row — a named Chief Medical Advisor and a named 503A pharmacy — but it's a men's-only platform, not a fit for every reader.
- Sema
- $229/mo (once-weekly injectable)
- Tirz
- $299/mo (once-weekly injectable)
- Coverage
- Multi-state
- Brand
- Compounded
- 06C72/ 100Index
Peter MD
Ranked #54One account across six verticals — TRT, ED, weight loss, GLP-1, men's hair loss and NAD+ — from a physician-prescribed telehealth brand running since 2021, at a renewal price ($249/mo tirzepatide) well above its own $149 first-month headline.
- Sema
- $149/mo first-time (Level 1), $139/mo returning (Level 2)
- Tirz
- $149 first month, then $249/mo billed quarterly
- Coverage
- Multi-state
- Brand
- Compounded
- 07C72/ 100Index
Synergy Rx
Ranked #53Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact — at prices its own site never shows.
- Sema
- From $199/mo
- Tirz
- From $349/mo
- Coverage
- Not disclosed
- Brand
- Yes
- 08C75/ 100Index
Rylo Health
Ranked #52Rylo Health is a compounded GLP-1/NAD+/peptide telehealth platform operating in all 50 states through Lone Star Virtual Health PLLC and dispensing via VialsRX in Houston, TX.
- Sema
- $149/mo (all doses, promotional rate, compounded)
- Tirz
- $249/mo (all doses, compounded)
- Coverage
- All 50 states
- Brand
- Compounded
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.