Head-to-head · Cost-Efficiency Index
Cost Plus Drugs vs Nouri
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Cost Plus Drugs
Cost-first shoppers who want the cheapest transparent-pricing brand-name Ozempic channel.
Visit Cost Plus DrugsNouri
Shoppers who want a flat any-dose price and are willing to prepay 6 months to get the lowest rate.
Visit NouriThe verdict
Cost Plus Drugs and Nouri tie on the Cost-Efficiency Index at 64/100, so neither wins outright on the numbers. For most shoppers we'd start with Cost Plus Drugs (ranked #177, a hair above #183) — Cost-first shoppers who want the cheapest transparent-pricing brand-name Ozempic channel. But Nouri is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Cost Plus Drugs.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Cost Plus Drugs | Nouri |
|---|---|---|
| Cost-Efficiency Index | 64/100 | 64/100 |
| Semaglutide / mo | $279/mo (brand Ozempic) | $175/mo (all doses, prepay plan, compounded) |
| Tirzepatide / mo | Not disclosed | $225/mo (all doses, prepay plan, compounded) |
| Semaglutide / yr (modeled) | $3,348 | $2,100 |
| Tirzepatide / yr (modeled) | — | $2,700 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #177 | #183 |
Cost Plus Drugs
64/100Where the value is
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
The tradeoffs
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
Nouri
64/100Where the value is
- 'Any dose, same price' means no dose-escalation surcharge — unlike most compounded-GLP-1 competitors
- Names a real, licensed 503A compounding pharmacy (F&F Pharmacies dba Jungle Jim's Pharmacy, Fairfield, OH) and a named prescribing physician (Dr. Michael Wasef, MD)
- Bundles nutrition planning, movement planning, and concierge care into every tier at no extra charge, per the site's own claim
The tradeoffs
- The advertised 'starting at' headline price ($120 semaglutide / $175 tirzepatide) is the 6-month PREPAY rate only — the true month-to-month price is 46% and 29% higher respectively ($175 / $225)
- The 30-day money-back guarantee explicitly excludes the monthly (no-prepay) plan
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.