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Head-to-head · Cost-Efficiency Index

CeliaRx vs Optimized Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #337

CeliaRx

Cost-first shoppers who want peptide-experienced buyers wanting a la carte purchases rather than a structured monthly weight-loss program.

Visit CeliaRx
VS
Grade C · #342

Optimized Health

Shoppers who want a simple, all-inclusive starting price with no separate visit or membership fee, in one of five served states.

Visit Optimized Health

The verdict

Too close to callGrade C vs C

CeliaRx and Optimized Health tie on the Cost-Efficiency Index at 55/100, so neither wins outright on the numbers. For most shoppers we'd start with CeliaRx (ranked #337, a hair above #342) — Cost-first shoppers who want peptide-experienced buyers wanting a la carte purchases rather than a structured monthly weight-loss program. But Optimized Health is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs CeliaRx.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
32

Price Transparency

86
64

Nationwide Access

24
42

Formulation Options

77
77

Clinical Oversight

67
76

Contract Flexibility

31
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecCeliaRxOptimized Health
Cost-Efficiency Index55/10055/100
Semaglutide / mo$299/mo (2 mg dose, compounded oral)$200/mo (starting dose, plus a separate fee, compounded)
Tirzepatide / mo$699/mo (34 mg dose, compounded)$250/mo (starting dose, bundle, compounded)
Semaglutide / yr (modeled)$3,588$2,400
Tirzepatide / yr (modeled)$8,388$3,000
CoverageCoverage not published5 states
Oral / sublingualYesYes
Brand-name accessCompounded onlyCompounded only
Rank here#337#342

CeliaRx

55/100

Where the value is

  • LegitScript seal displayed
  • Offers both injectable and oral-dissolving-tablet formats
  • Multiple dose tiers available for both drugs

The tradeoffs

  • Not primarily positioned as a weight-loss clinic -- broader peptide/longevity focus dilutes clinical weight-loss framing
  • No disclosed supply duration per SKU, so real monthly cost can't be confirmed from the site
Visit CeliaRx

Full CeliaRx review →

Optimized Health

55/100

Where the value is

  • Genuinely bundled pricing: the advertised $200/$250 figures are stated to include medication, monitoring, and provider care with 'no contracts'
  • LegitScript certified, with the verification link published on-site
  • HSA/FSA accepted

The tradeoffs

  • Single-provider practice: Mathew Hammons, PA-C is named on-site as 'The Only Licensed Prescriber,' with no backup clinician or named medical director disclosed
  • Telehealth is limited to just five states (Missouri, Iowa, Kansas, Utah, Washington) plus one in-person Joplin, MO clinic
Visit Optimized Health

Full Optimized Health review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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