Best-value alternatives
Alternatives to Optimized Health
Optimized Health scores 55/100 on our Cost-Efficiency Index (ranked #342 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.
- Our #1 pick01A94/ 100Index
CoreAge Rx
Ranked #1Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
- 02C55/ 100Index
Nucore Health
Ranked #341Nucore Health is a nationwide (all 50 states, per its own claim) DTC telehealth platform selling compounded semaglutide plus B12 at a flat $299/month regardless of dose, alongside anti-aging, sexual health, and hair-restoration products.
- Sema
- $299/mo (all doses, compounded)
- Tirz
- Not disclosed
- Coverage
- Multi-state
- Brand
- Compounded
- 03C55/ 100Index
Mint Medical Clinic
Ranked #340Mint Medical Clinic is primarily an in-person medical clinic with locations in Sandy and Layton, Utah.
- Sema
- $299/mo (starting dose, compounded)
- Tirz
- $299/mo (starting dose, compounded)
- Coverage
- 1 state
- Brand
- Compounded
- 04C55/ 100Index
MediRX
Ranked #339MediRx is a weight-loss telehealth storefront that white-labels OpenLoop Health's clinician network for actual prescribing and pharmacy fulfillment.
- Sema
- $149/mo (starting dose, compounded)
- Tirz
- $199/mo (starting dose, compounded)
- Coverage
- Multi-state
- Brand
- Compounded
- 05C55/ 100Index
Harmony Wellness Clinic
Ranked #338Harmony Wellness Clinic is a nurse-practitioner-led telehealth weight-loss clinic offering dose-tiered compounded semaglutide and tirzepatide (each bundled with B12) across a genuinely broad 40+ state telehealth network.
- Sema
- $200/mo (compounded)
- Tirz
- $250/mo (compounded)
- Coverage
- 36 states
- Brand
- Compounded
- 06C55/ 100Index
CeliaRx
Ranked #337CeliaRX is a peptide/longevity-focused telehealth shop that sells compounded semaglutide and tirzepatide (including an unusual oral-dissolving-tablet format) as discrete purchases rather than a clear monthly subscription.
- Sema
- $299/mo (2 mg dose, compounded oral)
- Tirz
- $699/mo (34 mg dose, compounded)
- Coverage
- Multi-state
- Brand
- Compounded
- 07C55/ 100Index
Call-On-Doc
Ranked #336Call-On-Doc is a telehealth platform that writes prescriptions for branded GLP-1s (Ozempic, Wegovy, Mounjaro, Zepbound, Saxenda) which patients then fill at their own pharmacy using their own insurance or cash price -- it does not sell or ship the medication itself.
- Sema
- Not disclosed
- Tirz
- Not disclosed
- Coverage
- All 50 states
- Brand
- Yes
- 08C55/ 100Index
Premium Health
Ranked #335Premium Health (premiumhealth.us) is a LegitScript-certified telehealth provider selling compounded semaglutide ($275/mo base, $375/mo at the higher labeled dose) and tirzepatide ($445/mo base, $595/mo at the higher labeled dose) as all-inclusive.
- Sema
- $275/mo (compounded)
- Tirz
- $445/mo (compounded)
- Coverage
- Multi-state
- Brand
- Compounded
Regulatory note: the FDA issued a warning letter to Premium Health Management Inc. dba Premium Health in February 2026. We still list and link to Premium Health; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.