Alternatives
Alternatives to Polly
Polly scores 66/100 on our Cost-Efficiency Index . Here are other programs to consider, each scored the same way. Partners are listed first.
Polly at a glance
- Semaglutide
- $135/week$585/mo equiv.
- Tirzepatide
- $199/week$862/mo equiv.
- Coverage
- All 50 states
- Brand-name GLP-1s
- No, compounded only
- Oral option
- No
8 of the 8 programs below list semaglutide for less than Polly's $585 a month. 8 of the 8 list tirzepatide for less than its $862 a month.
Polly's advertised $135 and $199 prices are billed weekly, not monthly, so the real monthly cost is roughly $585 for semaglutide and $862 for tirzepatide.
Best for: Shoppers who understand the pricing is billed weekly and want a flat, dose-independent recurring charge from a named pharmacy.
What Polly does well
- Names two specific 503A partner compounding pharmacies (Hallandale Pharmacy, VialsRx) rather than staying anonymous
- Nationwide all-50 access with flat pricing at every dose
- Displays a LegitScript certification seal
Why readers look for an alternative
- The headline $135/$199 prices are billed WEEKLY, not monthly — the real monthly-equivalent cost is roughly $585 (semaglutide) and $862 (tirzepatide)
- Compounded only — no brand-name or oral route
- Partner01A94/ 100Index
CoreAge Rx
CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Polly: $486/mo less for semaglutide · $713/mo less for tirzepatide
- 02C67/ 100Index
Lighter You
Lighter You lists compounded semaglutide and tirzepatide injections starting at $169 a month and GLP-1 tablets from $249, but its "start for just $99" banner matches no plan it lists.
- Sema
- $169/moStarting price, compounded
- Tirz
- $169/moStarting price, compounded
- Coverage
- Not published
- Brand
- Compounded
Compared with Polly: $416/mo less for semaglutide · $693/mo less for tirzepatide · offers an oral option
- 03C67/ 100Index
Auren Rx
Auren Rx sells compounded semaglutide at $179 a month and tirzepatide at $259 with no commitment, or $149 and $229 on subscribe and save, with the visit, medication and shipping in one price.
- Sema
- $179/moCompounded, month to month; $149/mo on subscribe and save
- Tirz
- $259/moCompounded, month to month; $229/mo on subscribe and save
- Coverage
- Not published
- Brand
- Compounded
Compared with Polly: $406/mo less for semaglutide · $603/mo less for tirzepatide
- 04C67/ 100Index
MD Total Wellness
MD Total Wellness is an in-person clinic in Brea, California, charging $299 a month for compounded semaglutide and $399 for tirzepatide at any dose, after a cheaper first month.
- Sema
- $299/moCompounded, any dose after a $199 first month
- Tirz
- $399/moCompounded, any dose after a $299 first month
- Coverage
- California only
- Brand
- Compounded
Compared with Polly: $286/mo less for semaglutide · $463/mo less for tirzepatide
- 05C67/ 100Index
RX Bella
Four routes priced from a floor on one page, a hero quoting the cheapest of them, and treatment pages that carry no price at all.
- Sema
- From $249/moFor the injection — a published floor, not a committed rate
- Tirz
- From $299/moFor the injection — the same floor treatment
- Coverage
- Multi-state
- Brand
- Compounded
Compared with Polly: $336/mo less for semaglutide · $563/mo less for tirzepatide · offers an oral option
- 06C67/ 100Index
Spry
Spry is a weight-loss and anti-aging telehealth brand, founded by Gabriel Mullins, Sara Yoder, and Tyler Bowman.
- Sema
- $199/moAll doses, compounded
- Tirz
- $299/moAll doses, compounded
- Coverage
- Multi-state
- Brand
- Yes
Compared with Polly: $386/mo less for semaglutide · $563/mo less for tirzepatide · also lists brand-name GLP-1s
- 07C67/ 100Index
InstaRX
InstaRx sells compounded semaglutide and tirzepatide at a single flat monthly price regardless of dose — $179/mo and $259/mo respectively — with free expedited shipping.
- Sema
- $179/mo
- Tirz
- $259/mo
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Polly: $406/mo less for semaglutide · $603/mo less for tirzepatide
- 08C67/ 100Index
Hello Alpha
Hello Alpha is a well-established women's telehealth brand that also genuinely prescribes FDA-approved branded GLP-1s (Wegovy, Ozempic, Mounjaro, Zepbound, and orforglipron/Foundayo) rather than compounded versions.
- Sema
- $79/moBrand Wegovy, plus a separate fee
- Tirz
- $79/moBrand Mounjaro, plus a separate fee
- Coverage
- Multi-state
- Brand
- Yes
Compared with Polly: $506/mo less for semaglutide · $783/mo less for tirzepatide · also lists brand-name GLP-1s · offers an oral option
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.