Head-to-head · Cost-Efficiency Index
ZYP Medical vs Call-On-Doc
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
ZYP Medical
Cost-first shoppers who want men in IA, NE, SD, MN, KS, CO or AZ wanting a low starter rate with an oral needle-free option.
Visit ZYP MedicalCall-On-Doc
Shoppers who already have insurance covering a branded GLP-1 and want a low-cost consult subscription to get the prescription written.
Visit Call-On-DocThe verdict
ZYP Medical takes it, leading the Cost-Efficiency Index 56 to 55. ZYP Medical is a men's-health-oriented telehealth practice now covering seven Midwest/Mountain states (recently adding Minnesota) with both injectable and oral (ODT) tirzepatide. Call-On-Doc still earns a C — Shoppers who already have insurance covering a branded GLP-1 and want a low-cost consult subscription to get the prescription written.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs ZYP Medical.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | ZYP Medical | Call-On-Doc |
|---|---|---|
| Cost-Efficiency Index | 56/100 | 55/100 |
| Semaglutide / mo | $150/mo (starting dose, 3 month plan, plus a separate fee, compounded) | Not disclosed |
| Tirzepatide / mo | $233/mo (starting dose, 3 month plan, plus a separate fee, compounded) | Not disclosed |
| Semaglutide / yr (modeled) | $1,800 | — |
| Tirzepatide / yr (modeled) | $2,796 | — |
| Coverage | 6 states | All 50 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #333 | #336 |
ZYP Medical
56/100Where the value is
- Offers a genuine needle-free oral tirzepatide (ODT) option, not just injectable
- Consult fee is disclosed and itemized ($50, or $29.99 for a shorter returning-patient visit)
- Recently expanded to 7 states (added Minnesota)
The tradeoffs
- Advertised $150/$233 prices are explicitly labeled 'starter plans (initial 3 months)' — what they become after 3 months is not published anywhere on the site
- One-time consult fee ($29.99-$50) is charged on top of the medication price and is non-refundable once the visit occurs
Call-On-Doc
55/100Where the value is
- LegitScript seal displayed, with 50-state coverage claimed via a state-selection dropdown
- Low-cost visit subscription tiers ($24.99-$49.99/mo) that include multiple free visits per month, cheaper than most one-off telehealth consult fees
- Explicitly lets patients use their own insurance at their own pharmacy, which can be dramatically cheaper than a self-pay compounded-GLP-1 subscription for insured patients
The tradeoffs
- No fixed medication price exists anywhere on the site — actual drug cost depends entirely on the patient's own insurance and pharmacy, so it cannot be compared apples-to-apples against competitors with a published price
- Uninsured or underinsured patients could pay full retail branded-drug price (often $1,000+/month) with no compounded fallback offered here
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.