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Head-to-head · Cost-Efficiency Index

Willow vs Arc-1

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #429

Willow

Cost-first shoppers who want an oral-tablet GLP-1 option at the same price as the injectable, with no annual commitment.

Visit Willow
VS
Grade C · #431

Arc-1

Shoppers comparing headline GLP-1 starting prices who will click into the specific product page rather than trust the homepage figure.

Visit Arc-1

The verdict

Winner · WillowGrade C vs C

Willow takes it, leading the Cost-Efficiency Index 49 to 48. Willow is a direct-to-consumer telehealth provider offering compounded semaglutide and tirzepatide in both injectable and oral-tablet form at identical prices per format. Arc-1 still earns a CShoppers comparing headline GLP-1 starting prices who will click into the specific product page rather than trust the homepage figure.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Willow.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
45

Price Transparency

54
54

Nationwide Access

24
24

Formulation Options

51
40

Clinical Oversight

79
72

Contract Flexibility

55
61

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecWillowArc-1
Cost-Efficiency Index49/10048/100
Semaglutide / moNot disclosedNot disclosed
Tirzepatide / moNot disclosedNot disclosed
Semaglutide / yr (modeled)
Tirzepatide / yr (modeled)
CoverageCoverage not publishedCoverage not published
Oral / sublingualYesNo
Brand-name accessCompounded onlyCompounded only
Rank here#429#431

Willow

49/100

Where the value is

  • Oral tablet formulations of both semaglutide and tirzepatide, priced identically to the injectable versions ($299/mo and $399/mo respectively) — a genuine format choice most compounded-drug competitors don't offer
  • Month-to-month billing with no prepay or annual term required to get the advertised rate
  • Named physician team publicly listed, including Chief Medical Officer Dr. Michael Green, MD, plus 11+ other credentialed MDs/DOs

The tradeoffs

  • Only 34 states served — notably narrower than WeightlessRx's 49-state footprint; residents of the other 16 states plus DC are excluded
  • Site states medication cost 'varies by dosage and prescription' but never discloses what a higher maintenance dose actually costs beyond the $299/$399 starting figures
Visit Willow

Full Willow review →

Arc-1

48/100

Where the value is

  • Both semaglutide and tirzepatide offered, with LegitScript Certified badge displayed and linked for verification
  • Free 1-3 day shipping and a free consultation stated as included, with no separate visit-fee line item found
  • Named founder physician (Dr. Todd Stearns) rather than an anonymous entity

The tradeoffs

  • The homepage price ($199.99/mo for both drugs) and each drug's own product page (tirzepatide shows $149/mo) do not agree — the number you see depends on which page you land on
  • Every dose variant on both product pages was shown as sold out/unavailable during this review, so the advertised price cannot currently be tied to a specific mg dose
Visit Arc-1

Full Arc-1 review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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