Head-to-head · Cost-Efficiency Index
VitaFusions IV vs Fifty 410
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
VitaFusions IV
Cost-first shoppers who want texas-area shoppers who want a flat, no-contract monthly GLP-1 price alongside an existing IV-therapy relationship.
Visit VitaFusions IVFifty 410
Cost-first shoppers who want a one-time-payment compounded tirzepatide bundle, understanding the 'per month' figure is really a 3-month lump sum.
Visit Fifty 410The verdict
VitaFusions IV takes it, leading the Cost-Efficiency Index 60 to 59. VitaFusions IV is a Dallas, TX-based IV-therapy and medical-weight-loss provider that does genuinely sell compounded semaglutide ($149/mo) and tirzepatide ($189/mo) at a flat, dose-independent monthly rate with no memberships or contracts. Fifty 410 still earns a C — Cost-first shoppers who want a one-time-payment compounded tirzepatide bundle, understanding the 'per month' figure is really a 3-month lump sum.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs VitaFusions IV.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | VitaFusions IV | Fifty 410 |
|---|---|---|
| Cost-Efficiency Index | 60/100 | 59/100 |
| Semaglutide / mo | $149/mo (all doses, contract term, plus a separate fee, compounded) | $199/mo (all doses, compounded) |
| Tirzepatide / mo | $189/mo (all doses, contract term, compounded) | $133/mo (starting dose, 3-month plan, compounded) |
| Semaglutide / yr (modeled) | $1,788 | $2,388 |
| Tirzepatide / yr (modeled) | $2,268 | $1,596 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #259 | #263 |
VitaFusions IV
60/100Where the value is
- Flat, dose-independent monthly price on both drugs — 'the price you start with is the price you keep,' explicitly no increases as dose is titrated up
- Named dispensing pharmacy (New Solutions Functional Wellness Pharmacy, with a listed phone number)
- No memberships, contracts, or autodrafts — genuinely pay-as-you-go per the site's own language
The tradeoffs
- No evidence of service outside Texas — the site speaks only of Dallas and 'across Texas,' with no states-served list
- No named prescriber or medical director anywhere on the site
Fifty 410
59/100Where the value is
- No recurring subscription — you pay once per order and are not auto-billed
- Transparent per-tier tirzepatide totals ($399/$499/$549) shown alongside the per-month math, so the real charge is visible if you read past the headline
- Free overnight/2-day shipping and refrigerated packaging included in every tier
The tradeoffs
- Tirzepatide's advertised '$133/month' is a 3-month prepay of $399 charged in one transaction, not a monthly recurring price — the cheapest advertised number is not what most shoppers will assume
- Semaglutide has no discounted multi-month tier and, at $199 flat, actually costs more per month than tirzepatide's cheapest bundle
Regulatory note: the FDA issued a warning letter to Aspen Aesthetics dba Fifty 410 in February 2026. We still list and link to Fifty 410; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.