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Head-to-head · Cost-Efficiency Index

VevaRX vs Fifty 410

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #261

VevaRX

Readers in one of the 36 states it names who will confirm the charge in writing before submitting an intake.

Visit VevaRX
VS
Grade C · #263

Fifty 410

Cost-first shoppers who want a one-time-payment compounded tirzepatide bundle, understanding the 'per month' figure is really a 3-month lump sum.

Visit Fifty 410

The verdict

Winner · VevaRXGrade C vs C

VevaRX takes it, leading the Cost-Efficiency Index 60 to 59. VevaRX sells compounded semaglutide at $189 a month and tirzepatide only as a $467 quarterly plan with a three-month minimum, on a site that prints at least eight mutually contradictory prices for its own products. Fifty 410 still earns a CCost-first shoppers who want a one-time-payment compounded tirzepatide bundle, understanding the 'per month' figure is really a 3-month lump sum.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs VevaRX.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

44
57

Price Transparency

78
94

Nationwide Access

66
24

Formulation Options

66
66

Clinical Oversight

60
68

Contract Flexibility

43
37

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecVevaRXFifty 410
Cost-Efficiency Index60/10059/100
Semaglutide / mo$189/month month-to-month (the same page also prints $167/month and a $467 three-month total)$199/mo (all doses, compounded)
Tirzepatide / mo$155.67/mo equivalent — VevaRX bills $467 every three months on a three-month minimum and publishes no monthly plan$133/mo (starting dose, 3-month plan, compounded)
Semaglutide / yr (modeled)$2,268$2,388
Tirzepatide / yr (modeled)$1,860$1,596
Coverage36 statesCoverage not published
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank here#261#263

VevaRX

60/100

Where the value is

  • Enumerates the 36 states it serves by name rather than making an unqualified nationwide claim
  • States what the tirzepatide price covers — the treatment, the supplies, the provider visit and two-to-three-day shipping
  • Publishes a monthly semaglutide option alongside the quarterly plan, which its tirzepatide program does not offer

The tradeoffs

  • The semaglutide page carries four prices, two of which belong to tirzepatide: $189 a month, $399 for three months, $167 a month and a $467 total
  • The tirzepatide page's own arithmetic is wrong — it calls $467 over three months "equivalent to $149 per month", when it is $155.67, a figure the semaglutide page states correctly
Visit VevaRX

Full VevaRX review →

Fifty 410

59/100

Where the value is

  • No recurring subscription — you pay once per order and are not auto-billed
  • Transparent per-tier tirzepatide totals ($399/$499/$549) shown alongside the per-month math, so the real charge is visible if you read past the headline
  • Free overnight/2-day shipping and refrigerated packaging included in every tier

The tradeoffs

  • Tirzepatide's advertised '$133/month' is a 3-month prepay of $399 charged in one transaction, not a monthly recurring price — the cheapest advertised number is not what most shoppers will assume
  • Semaglutide has no discounted multi-month tier and, at $199 flat, actually costs more per month than tirzepatide's cheapest bundle
Visit Fifty 410

Full Fifty 410 review →

Regulatory note: the FDA issued a warning letter to Aspen Aesthetics dba Fifty 410 in February 2026. We still list and link to Fifty 410; you should know the letter is on the public record before you decide.

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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