Head-to-head · Cost-Efficiency Index
Tyde Wellness vs Dr. Gillis' Wellness Center
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Tyde Wellness
Shoppers who want a named, LegitScript-certified five-pharmacy compounded-GLP-1 network with no long-term commitment.
Visit Tyde WellnessDr. Gillis' Wellness Center
Cost-first shoppers who want maine-based or Central-Maine patients wanting an experienced, board-certified physician offering sublingual ODT GLP-1 options.
Visit Dr. Gillis' Wellness CenterThe verdict
Tyde Wellness takes it, leading the Cost-Efficiency Index 66 to 65. Tyde Wellness is a compounded-GLP-1 and longevity telehealth platform (weight loss, HRT, hair, longevity) serving all 50 states, with semaglutide starting at $149/mo and tirzepatide at $249/mo. Dr. Gillis' Wellness Center still earns a C — Cost-first shoppers who want maine-based or Central-Maine patients wanting an experienced, board-certified physician offering sublingual ODT GLP-1 options.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Tyde Wellness.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Tyde Wellness | Dr. Gillis' Wellness Center |
|---|---|---|
| Cost-Efficiency Index | 66/100 | 65/100 |
| Semaglutide / mo | $149/mo (microdose tier, starting dose, compounded) | $250/mo (starting dose, compounded oral) |
| Tirzepatide / mo | $249/mo (microdose tier, starting dose, compounded) | $325/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $1,788 | $3,000 |
| Tirzepatide / yr (modeled) | $2,988 | $3,900 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #153 | #159 |
Tyde Wellness
66/100Where the value is
- All 50 states served, confirmed via the site's own full state list
- Five named 503A pharmacy partners with cities — unusually specific for this market
- LegitScript certified, with a verification badge displayed
The tradeoffs
- No visible per-dose price ladder — the $149/$249 is a 'starting at' figure, and whether a higher titrated dose costs more could not be confirmed without completing the gated intake
- No visit or membership fee is disclosed either way — it's unclear whether $149/$249 is genuinely all-in or medication-only
Dr. Gillis' Wellness Center
65/100Where the value is
- Led by a board-certified physician/surgeon with 25+ years of experience per the practice's own materials
- Offers a broad GLP-1 menu — semaglutide, tirzepatide, and retatrutide — in both injectable and needle-free sublingual ODT form
- No long-term contracts; flexible weekly, bi-weekly, or monthly dosing cadence
The tradeoffs
- The advertised '$149 starting dose' is just that — a starting dose. The practice's own dedicated pricing page lists semaglutide 'Starting at $250/Month' and tirzepatide 'Starting at $325/month,' both well above the promotional figure
- Nationwide/all-50-states coverage could not be confirmed on the practice's own site; third-party directories describe it as a Central Maine practice
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.