Head-to-head · Cost-Efficiency Index
Tryozi vs SexyMD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Tryozi
Shoppers comparing standing rates rather than first-month promo banners.
Visit TryoziSexyMD
Readers willing to commit 48 weeks up front, where the advertised figure is the one actually charged.
Visit SexyMDThe verdict
Tryozi and SexyMD tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers. For most shoppers we'd start with Tryozi (ranked #112, a hair above #119) — Shoppers comparing standing rates rather than first-month promo banners. But SexyMD is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Tryozi.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Tryozi | SexyMD |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $279/mo (first-month rate, compounded) | $269/mo on the four-week plan (the site's "from $199" is the 48-week commitment rate) |
| Tirzepatide / mo | $379/mo (first-month rate, compounded) | $369/mo on the four-week plan (the site's "from $299" is the 48-week commitment rate) |
| Semaglutide / yr (modeled) | $3,348 | $3,228 |
| Tirzepatide / yr (modeled) | $4,548 | $4,428 |
| Coverage | All 50 states | 47 states |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #112 | #119 |
Tryozi
68/100Where the value is
- The site voluntarily discloses its own standing rate ('normally $279/mo') right beside the promo price, which is more transparent than providers that hide it until checkout
- Base labs, consult, medication, and shipping stated as bundled with no hidden fees
- Four named 503A compounding pharmacies rather than one anonymous partner
The tradeoffs
- The prominent $139/$189 banner price is a one-time 50%-off first month only — the real ongoing cost is exactly double, $279/$379/month
- No named individual prescriber or medical director found on the site
SexyMD
68/100Where the value is
- Publishes a full four-rung price table for each molecule on its product pages, before any intake
- States both pharmacy classes it uses and discloses that a prescription may be routed to, and transferred between, any pharmacy in that network
- Names the professional entities its prescribers work through, rather than referring only to licensed providers
The tradeoffs
- Every headline on the site quotes the 48-week rate: "from $199 per month" against a four-week price of $269, and "from $299" against $369, with an asterisk that resolves to no footnote
- The same footer block says both "available in all 50 states" and "available in all states except Arkansas, Mississippi, and New Jersey", on all eleven pages
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.