Head-to-head · Cost-Efficiency Index
TRYM Health vs TD Tele-Doc Weight Loss
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
TRYM Health
Shoppers willing to prepay a full year upfront for the lowest published per-day compounded GLP-1 rate.
Visit TRYM HealthTD Tele-Doc Weight Loss
Patients with Medicare or major insurance who want a local Richmond, VA-area virtual weight-loss clinic to bill through their plan.
Visit TD Tele-Doc Weight LossThe verdict
TRYM Health and TD Tele-Doc Weight Loss tie on the Cost-Efficiency Index at 66/100, so neither wins outright on the numbers. For most shoppers we'd start with TRYM Health (ranked #144, a hair above #151) — Shoppers willing to prepay a full year upfront for the lowest published per-day compounded GLP-1 rate. But TD Tele-Doc Weight Loss is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs TRYM Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | TRYM Health | TD Tele-Doc Weight Loss |
|---|---|---|
| Cost-Efficiency Index | 66/100 | 66/100 |
| Semaglutide / mo | $96/mo (all doses, 12 month plan, compounded) | $145/mo (compounded) |
| Tirzepatide / mo | $126/mo (all doses, 12 month plan, compounded) | Not disclosed |
| Semaglutide / yr (modeled) | $1,152 | $1,740 |
| Tirzepatide / yr (modeled) | $1,512 | — |
| Coverage | Coverage not published | 2 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #144 | #151 |
TRYM Health
66/100Where the value is
- Full tiered pricing table published on-site — every commitment length and its total cost is transparent before intake
- Multi-dose vials cover all doses up to 15mg/week at every tier, so no separate charge for titrating up
- 'ZERO membership fees, shipping costs, hidden anything' per the site's own copy
The tradeoffs
- The widely-quoted '$3.20/day' and '$4.20/day' rates require a $1,150 or $1,500 one-time 12-month prepayment — the real month-to-month price with no commitment is 43-56% higher ($150/$180)
- No compounding pharmacy is named anywhere on the site
Regulatory note: the FDA issued a warning letter to TRYM Health, Inc. dba TRYM Health in September 2025. We still list and link to TRYM Health; you should know the letter is on the public record before you decide.
TD Tele-Doc Weight Loss
66/100Where the value is
- Accepts Medicare and most major insurance plans, potentially lowering real out-of-pocket cost for covered patients
- Displays a LegitScript verification badge
- Straightforward semaglutide-specific landing page
The tradeoffs
- The '$145 starting at' price is insurance-contingent, not a flat cash-pay rate
- No tirzepatide pricing found
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.