Head-to-head · Cost-Efficiency Index
CoreAge Rx vs TRYM Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
CoreAge Rx
Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.
Visit CoreAge RxTRYM Health
Shoppers willing to prepay a full year upfront for the lowest published per-day compounded GLP-1 rate.
Visit TRYM HealthThe verdict
CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 66. Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. TRYM Health still earns a C — Shoppers willing to prepay a full year upfront for the lowest published per-day compounded GLP-1 rate.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | CoreAge Rx | TRYM Health |
|---|---|---|
| Cost-Efficiency Index | 94/100 | 66/100 |
| Semaglutide / mo | $99/mo | $96/mo (all doses, 12 month plan, compounded) |
| Tirzepatide / mo | $149/mo | $126/mo (all doses, 12 month plan, compounded) |
| Semaglutide / yr (modeled) | $1,188 | $1,152 |
| Tirzepatide / yr (modeled) | $1,788 | $1,512 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #1 | #144 |
CoreAge Rx
94/100Where the value is
- Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
- Both compounded semaglutide and tirzepatide on one account at published prices
- Available in all 50 states — no coverage gamble
The tradeoffs
- Not the rock-bottom sticker price — 30 of the 381 priced semaglutide programs we track list a cheaper figure, though most attach a term or a step-up that CoreAge does not
- No FDA-approved brand-name option (compounded only)
TRYM Health
66/100Where the value is
- Full tiered pricing table published on-site — every commitment length and its total cost is transparent before intake
- Multi-dose vials cover all doses up to 15mg/week at every tier, so no separate charge for titrating up
- 'ZERO membership fees, shipping costs, hidden anything' per the site's own copy
The tradeoffs
- The widely-quoted '$3.20/day' and '$4.20/day' rates require a $1,150 or $1,500 one-time 12-month prepayment — the real month-to-month price with no commitment is 43-56% higher ($150/$180)
- No compounding pharmacy is named anywhere on the site
Regulatory note: the FDA issued a warning letter to TRYM Health, Inc. dba TRYM Health in September 2025. We still list and link to TRYM Health; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.