Head-to-head · Cost-Efficiency Index
Trimi Health vs Pepti
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Trimi Health
Shoppers who can pay a full year up front, and anyone else who will budget for the month-to-month price instead of the headline.
Visit Trimi HealthPepti
Shoppers who want to see the price of every dose step before they start, with no membership fee on top.
Visit PeptiThe verdict
Pepti takes it, leading the Cost-Efficiency Index 80 to 78. Pepti sells compounded semaglutide from $99 a month at the starting dose and tirzepatide from $159, with every dose step priced on the page and the doctor, labs and shipping included. Trimi Health still earns a C — Shoppers who can pay a full year up front, and anyone else who will budget for the month-to-month price instead of the headline.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Pepti.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Trimi Health | Pepti |
|---|---|---|
| Cost-Efficiency Index | 78/100 | 80/100 |
| Semaglutide / mo | $175/moMonth-to-month ($99/mo only on a 12-month prepay) | $99/mo0.25 mg starting dose, compounded; $109–$199 at higher doses |
| Tirzepatide / mo | $235/moMonth-to-month ($125/mo only on a 12-month prepay) | $159/mo2.5 mg starting dose, compounded; $179–$319 at higher doses |
| Semaglutide / yr (modeled) | $2,100 | $1,28713 charges |
| Tirzepatide / yr (modeled) | $2,820 | $2,06713 charges |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #32 | #38 |
Trimi Health
78/100Where the value is
- All four plan lengths are priced on its pricing page: semaglutide is $175 monthly, $145 quarterly, $120 on six months and $99 on a year
- Tirzepatide follows the same pattern: $235 monthly, $199 quarterly, $175 on six months and $125 on a year
- Price is flat at every dose, so titrating up does not raise the bill
The tradeoffs
- The advertised $99 and $125 need a full year paid up front, $1,188 or $1,500; month to month costs $175 and $235
- Compounded only, with no brand-name or oral option
Pepti
80/100Where the value is
- Every dose has its own published price: semaglutide runs $99 to $199 and tirzepatide $159 to $319
- No membership fee; the medication price includes physician review, dose adjustments and free shipping
- Names a reviewing physician and a dispensing pharmacy, Olympia Pharmacy
The tradeoffs
- The price rises as your dose goes up, so the $99 starting figure covers only the first step of semaglutide
- It bills every 28 days rather than monthly, which adds up to 13 charges a year
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.