Head-to-head · Cost-Efficiency Index
Trimi Health vs NP2GO
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Trimi Health
Shoppers who can pay a full year up front, where the annual rate is genuinely among the cheapest all-50 tickets — and who will otherwise budget for the month-to-month rate.
Visit Trimi HealthNP2GO
Shoppers inside its 40 served states who want both molecules disclosed and will vet the pharmacy themselves.
Visit NP2GOThe verdict
NP2GO takes it, leading the Cost-Efficiency Index 79 to 78. $150 semaglutide and $250 tirzepatide across 40 states — solid regional reach and full price disclosure, but the coverage gap and missing LegitScript verification cap the value. Trimi Health still earns a C — Shoppers who can pay a full year up front, where the annual rate is genuinely among the cheapest all-50 tickets — and who will otherwise budget for the month-to-month rate.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs NP2GO.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Trimi Health | NP2GO |
|---|---|---|
| Cost-Efficiency Index | 78/100 | 79/100 |
| Semaglutide / mo | $175/mo month-to-month ($99/mo only on a 12-month prepay) | $150/mo |
| Tirzepatide / mo | $235/mo month-to-month ($125/mo only on a 12-month prepay) | $250/mo |
| Semaglutide / yr (modeled) | $2,100 | $1,800 |
| Tirzepatide / yr (modeled) | $2,820 | $3,000 |
| Coverage | All 50 states | AK, AZ, AR, CA, CO, CT, DE, DC, FL, HI, ID, IL, IA, KS, KY, ME, MD, MA, MI, MN, MT, NE, NV, NH, NJ, NM, NY, ND, OK, OR, PA, RI, SD, TX, UT, VT, VA, WA, WV, WY |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #30 | #33 |
Trimi Health
78/100Where the value is
- Publishes every term rung openly — annual, six-month, quarterly and monthly are all priced on the page rather than revealed at checkout
- Price is flat at every dose, so titrating up does not raise the bill
- Both molecules available on one account, nationwide, with no enrollment or consultation fee
The tradeoffs
- The advertised $99 and $125 rates require a full year paid up front; month-to-month costs $175 and $235, a 77% and 88% premium
- No public LegitScript certification, so pharmacy oversight is harder to independently verify
NP2GO
79/100Where the value is
- Both molecules disclosed — $150 semaglutide / $250 tirzepatide — for straightforward cost modeling
- Broad 40-state footprint — wider than most non-nationwide operators
- Flat, predictable pricing
The tradeoffs
- 40 states, not all 50 — a coverage gamble that dents its access score
- Not LegitScript-certified — oversight harder to verify
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.