Head-to-head · Cost-Efficiency Index
Trillium Meds vs Freeley
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Trillium Meds
Shoppers who want compounded GLP-1 in all 50 states with a real month-to-month option and a cheaper 3-month prepay.
Visit Trillium MedsFreeley
Shoppers ready to commit to a year or more of compounded GLP-1 treatment in exchange for a lower monthly rate that stays the same at every dose.
Visit FreeleyThe verdict
Trillium Meds and Freeley tie on the Cost-Efficiency Index at 73/100, so neither wins outright on the numbers, so choose on fit. Trillium Meds: Shoppers who want compounded GLP-1 in all 50 states with a real month-to-month option and a cheaper 3-month prepay. Freeley: Shoppers ready to commit to a year or more of compounded GLP-1 treatment in exchange for a lower monthly rate that stays the same at every dose.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Trillium Meds.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Trillium Meds | Freeley |
|---|---|---|
| Cost-Efficiency Index | 73/100 | 73/100 |
| Semaglutide / mo | $159/moAll doses, compounded | $299/moCompounded, month to month; $199/mo on the 12-month plan, $179/mo on 24 months |
| Tirzepatide / mo | $249/moAll doses, compounded | $399/moCompounded, month to month; $299/mo on the 12-month plan, $269/mo on 24 months |
| Semaglutide / yr (modeled) | $1,908 | $3,588 |
| Tirzepatide / yr (modeled) | $2,988 | $4,788 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #89 | #94 |
Trillium Meds
73/100Where the value is
- Discloses both a real month-to-month rate ($159/$249) and the 3-month prepay rate, rather than only advertising the lower prepay number
- LegitScript certified, all 50 states plus Puerto Rico, with a real street address published
- Syringes and alcohol wipes included; Klarna and Affirm financing available
The tradeoffs
- The lowest advertised rate ($119/mo semaglutide, ~$200/mo tirzepatide) requires a $357 or $599 upfront 3-month payment, not a standing monthly charge
- The site refers to partner pharmacies but doesn't name them, so ask which pharmacy will fill your prescription
Freeley
73/100Where the value is
- The full plan ladder for semaglutide is printed on the weight-loss page before any quiz: $299 for one month, $259 on 3 months, $229 on 6, $199 on 12 and $179 on 24
- The monthly price is flat at every dose, and it includes the physician consultation, the medication and shipping with no membership fee
- Names Strive Pharmacy, a 503A compounding pharmacy, as its dispensing partner and lists the pharmacy's contact details
The tradeoffs
- The homepage and pricing page lead with $199 and $179 a month, which are 12- and 24-month plan rates; month to month costs $299 for semaglutide and $399 for tirzepatide
- The pricing page says its $179 figure is on the 24-month plan while the footnote beside it says the 12-month plan, so check which plan you are being quoted at checkout
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.