Head-to-head · Cost-Efficiency Index
TMates vs MadeMed
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
TMates
Shoppers who want a flat price at every dose, with an oral semaglutide option and a provider who can also prescribe brand Wegovy or Zepbound.
Visit TMatesMadeMed
Shoppers comfortable paying three months at a time who want one flat price at every dose, or a no-needle sublingual semaglutide tablet.
Visit MadeMedThe verdict
TMates and MadeMed tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers, so choose on fit. TMates: Shoppers who want a flat price at every dose, with an oral semaglutide option and a provider who can also prescribe brand Wegovy or Zepbound. MadeMed: Shoppers comfortable paying three months at a time who want one flat price at every dose, or a no-needle sublingual semaglutide tablet.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs TMates.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | TMates | MadeMed |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $249/moMonth to month, same price at every dose, compounded | $239/moQuarterly plan, billed $717 every 3 months, same price at every dose, compounded |
| Tirzepatide / mo | $297/moMonth to month, same price at every dose, compounded | $399/moQuarterly plan, billed $1,197 every 3 months, same price at every dose, compounded |
| Semaglutide / yr (modeled) | $2,988 | $2,868 |
| Tirzepatide / yr (modeled) | $3,564 | $4,788 |
| Coverage | Not published ("most states") | 23 states |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Yes | Compounded only |
| Rank here | #160 | #161 |
TMates
68/100Where the value is
- Each product page lists every plan: semaglutide is $249 for one month, $650 for three, $1,050 for six and $1,900 for twelve; tirzepatide is $297, $800, $1,299 and $1,999
- The price covers the medication, telemedicine visits and coaching, and stays the same at every dose
- Semaglutide comes as a weekly injection or an oral option, and brand Wegovy or Zepbound can be prescribed for $99 a month to fill at your own pharmacy
The tradeoffs
- The "from $158" and "from $167" category prices are 12-month prepaid rates; month to month is $249 and $297
- No refund once your prescription is sent to the pharmacy
MadeMed
68/100Where the value is
- One flat price at every dose, printed dose by dose on each product page
- Offers sublingual semaglutide tablets ($219 a month quarterly) and oral tirzepatide alongside the injections
- You can cancel or pause in one click from your dashboard, and it emails you 7 days before every charge
The tradeoffs
- There is no monthly plan; the shortest commitment is three months, billed up front
- Injectable semaglutide is offered in only 23 states, fewer than the 40 the service lists overall, so check your state on the product page
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.