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WeighLab

TMates vs CLYR Health

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

TMates

Provider comparison

Shoppers who want a flat price at every dose, with oral options for both molecules and a provider who can also prescribe brand Wegovy or Zepbound.

Semaglutide / month
$249/moMonth to month, same price at every dose, compounded
Tirzepatide / month
$297/moMonth to month, same price at every dose, compounded
Index 68/100 · Grade CChecked October 2026

CLYR Health

Provider comparison

Patients comparing one-time supplies who want dose-level prices before intake and will resolve the conflicting refund terms with support.

Semaglutide / month
$169Per 28 days (one-time 0.4 mg weekly vial, compounded)
Tirzepatide / month
$249Per month supply (5 mg weekly; first 2.5 mg month $149, compounded)
Index 67/100 · Grade CChecked October 2026

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The comparison in brief

TMates has the higher Cost-Efficiency Index: 68/100 versus 67/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

TMates
Not published ("most states")
CLYR Health
Coverage not published

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

TMates

CLYR Health

Semaglutide / month
TMates: $249/moMonth to month, same price at every dose, compounded
CLYR Health: $169Per 28 days (one-time 0.4 mg weekly vial, compounded)
Tirzepatide / month
TMates: $297/moMonth to month, same price at every dose, compounded
CLYR Health: $249Per month supply (5 mg weekly; first 2.5 mg month $149, compounded)
Semaglutide / year (modeled)
TMates: $2,988
CLYR Health: $2,19713 charges
Tirzepatide / year (modeled)
TMates: $3,564
CLYR Health: $2,988
State availability
TMates: Not published ("most states")
CLYR Health: Coverage not published
Oral / sublingual option listed
TMates: Yes
CLYR Health: Yes
Brand-name access listed
TMates: Yes
CLYR Health: Yes
Provider facts checked
TMates: October 2026
CLYR Health: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

TMates

Shoppers who want a flat price at every dose, with oral options for both molecules and a provider who can also prescribe brand Wegovy or Zepbound.

Reasons to consider it

  • Each product page lists every plan: semaglutide is $249 for one month, $650 for three, $1,050 for six and $1,900 for twelve; tirzepatide is $297, $800, $1,299 and $1,999
  • The price covers the medication, telemedicine visits and coaching, and stays the same at every dose
  • Semaglutide and tirzepatide each come as a weekly injection or an oral option at the same plan prices, and brand Wegovy or Zepbound can be prescribed for $99 a month to fill at your own pharmacy

What to weigh up

  • The "from $158" and "from $167" category prices are 12-month prepaid rates; month to month is $249 and $297
  • No refund once your prescription is sent to the pharmacy
  • No state list: one page says it ships to "most states" and another says "50+ states"

CLYR Health

Patients comparing one-time supplies who want dose-level prices before intake and will resolve the conflicting refund terms with support.

Reasons to consider it

  • Publishes dose-level prices before the questionnaire
  • Includes clinician review, supplies and shipping in the injection price
  • Names MD Integrations as a prescribing group

What to weigh up

  • Semaglutide costs $169/$199/$229 per 28-day vial as dose rises; a year of continuous supply takes about 13 vials
  • Tirzepatide starts at $149, then costs $249 at 5 mg, $299 at 10 mg and $329 at 12.5 mg for a single-month supply
  • Product pages promise refunds if ineligible, while general terms say fees are non-refundable and discuss recurring subscriptions

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

TMatesCLYR Health
Normalized Cost/Month
TMates:
66/100
CLYR Health:
72/100
Price Transparency
TMates:
94/100
CLYR Health:
78/100
Nationwide Access
TMates:
24/100
CLYR Health:
24/100
Formulation Options
TMates:
90/100
CLYR Health:
95/100
Clinical Oversight
TMates:
73/100
CLYR Health:
87/100
Contract Flexibility
TMates:
67/100
CLYR Health:
45/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.