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Head-to-head · Cost-Efficiency Index

Teleios Health vs AlyveRx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #170

Teleios Health

Shoppers comfortable calling or messaging before committing, since public pricing detail is minimal.

Visit Teleios Health
VS
Grade C · #173

AlyveRx

Shoppers who specifically want a needle-free sublingual GLP-1 option alongside standard injections on the same platform.

Visit AlyveRx

The verdict

Winner · Teleios HealthGrade C vs C

Teleios Health takes it, leading the Cost-Efficiency Index 65 to 64. Teleios Health markets itself as a physician-led GLP-1 telehealth provider offering both compounded semaglutide and tirzepatide. AlyveRx still earns a CShoppers who specifically want a needle-free sublingual GLP-1 option alongside standard injections on the same platform.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Teleios Health.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

91
66

Price Transparency

94
78

Nationwide Access

24
24

Formulation Options

53
90

Clinical Oversight

49
71

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecTeleios HealthAlyveRx
Cost-Efficiency Index65/10064/100
Semaglutide / mo$99/mo (all doses, compounded)$183/mo (starting dose, compounded)
Tirzepatide / moNot disclosed$283/mo (starting dose, compounded)
Semaglutide / yr (modeled)$1,188$2,196
Tirzepatide / yr (modeled)$3,396
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoYes
Brand-name accessCompounded onlyYes
Rank here#170#173

Teleios Health

65/100

Where the value is

  • Advertises a low $99/mo headline starting price, undercutting most compounded-GLP-1 competitors on paper
  • Explicitly brands itself as 'physician-led,' setting an expectation of clinician oversight
  • Discloses the standard compounded-medication FDA disclaimer up front rather than burying it

The tradeoffs

  • No dose amount, drug, or inclusion breakdown is published for the $99/mo figure
  • No visit fee, membership fee, or shipping fee disclosure could be found anywhere on the site
Visit Teleios Health

Full Teleios Health review →

AlyveRx

64/100

Where the value is

  • Offers a genuinely needle-free sublingual delivery option (PermeAct) for both semaglutide and tirzepatide, not just injections
  • Also carries brand-name Ozempic, Wegovy, and Mounjaro for patients who want an FDA-approved product
  • All four price points (injection and drops, both drugs) are published upfront on the homepage before intake

The tradeoffs

  • The dataset's previous $249/mo tirzepatide figure is the SUBLINGUAL DROPS price, not the standard injection ($283/mo) — confirm which form a quoted price refers to
  • Sublingual PermeAct absorption relies on the company's own proprietary technology claims and is not FDA-reviewed for weight-loss efficacy
Visit AlyveRx

Full AlyveRx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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