Head-to-head · Cost-Efficiency Index
Strut Health vs NewSelf
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Strut Health
Anyone optimizing total monthly outlay who will keep an auto-refill running, and anyone whose real objection is the needle.
Visit Strut HealthNewSelf
Budget shoppers who want a verified all-50 program and one of the lowest disclosed tirzepatide prices in the value tier.
Visit NewSelfThe verdict
Strut Health and NewSelf tie on the Cost-Efficiency Index at 87/100, so neither wins outright on the numbers. For most shoppers we'd start with Strut Health (ranked #5, a hair above #11) — Anyone optimizing total monthly outlay who will keep an auto-refill running, and anyone whose real objection is the needle. But NewSelf is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Strut Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Strut Health | NewSelf |
|---|---|---|
| Cost-Efficiency Index | 87/100 | 87/100 |
| Semaglutide / mo | From $99/mo sublingual, $149/mo injectable | $100/mo |
| Tirzepatide / mo | From $199/mo either route | $144/mo |
| Semaglutide / yr (modeled) | $1,188 | $1,200 |
| Tirzepatide / yr (modeled) | $2,388 | $1,728 |
| Coverage | 49 states (not Arkansas) | All 50 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #5 | #11 |
Strut Health
87/100Where the value is
- $99/mo for sublingual semaglutide is among the lowest disclosed rates we track; tirzepatide is $199 either route
- Sublingual lozenges for both molecules at the same price as the injection
- Free physician visit, free shipping and free follow-up care included rather than billed separately
The tradeoffs
- The $99 and $149 headline figures require auto-refill — a one-off order costs more, so the true cost depends on staying subscribed
- Asynchronous by design: their FAQ notes some states need no phone consultation, so you may never speak to the prescriber
Regulatory note: the FDA issued a warning letter to Strut Health, LLC dba Strut in February 2026. We still list and link to Strut Health; you should know the letter is on the public record before you decide.
NewSelf
87/100Where the value is
- $100 semaglutide / $144 tirzepatide — one of the cheapest verified combined prices in the ranking
- Nationwide all-50 coverage with both molecules published up front
- LegitScript-certified pharmacy behind the low price
The tradeoffs
- Compounded only — no brand-name or oral option
- Newer consumer brand with a thin public track record
Regulatory note: the FDA issued a warning letter to NewSelf Limited dba NewSelf in February 2026. We still list and link to NewSelf; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.