Head-to-head · Cost-Efficiency Index
Sprout Health vs Trellis Vitality
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Sprout Health
Price-conscious shoppers who want a quick online intake and don't mind a subscription that bills every four weeks.
Visit Sprout HealthTrellis Vitality
Shoppers who want a low month-to-month GLP-1 price that holds at every dose, with no membership or consultation fee.
Visit Trellis VitalityThe verdict
Trellis Vitality takes it, leading the Cost-Efficiency Index 82 to 80. Trellis Vitality charges $150 a month for compounded semaglutide and $199 for tirzepatide at every dose, with a published table showing small discounts on three- and six-month plans. Sprout Health still earns a B− — Price-conscious shoppers who want a quick online intake and don't mind a subscription that bills every four weeks.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Trellis Vitality.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Sprout Health | Trellis Vitality |
|---|---|---|
| Cost-Efficiency Index | 80/100 | 82/100 |
| Semaglutide / mo | $149 per 4 weeks$99/mo on a prepaid 12-month plan | $150/moCompounded, month to month; same price at every dose |
| Tirzepatide / mo | $199 per 4 weeks$149/mo on a prepaid 12-month plan | $199/moCompounded, month to month; same price at every dose |
| Semaglutide / yr (modeled) | $1,93713 charges | $1,800 |
| Tirzepatide / yr (modeled) | $2,58713 charges | $2,388 |
| Coverage | 44 states (not AL, AR, CA, LA, MS or ND) | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #24 | #29 |
Sprout Health
80/100Where the value is
- Prices are on the homepage before you start: $149 or $199 every four weeks, or $1,188 and $1,788 for a prepaid year
- A licensed clinician reviews your intake, and most prescriptions reach the pharmacy within two business days
- Sprout names its dispensing pharmacies, Foothills Pharmacy and Promise Pharmacy, in its terms
The tradeoffs
- Billing runs every four weeks, so the monthly plan is 13 charges a year, about $1,937 on semaglutide and $2,587 on tirzepatide
- Cancel after a provider has reviewed your case and you lose a $50 review fee; once the prescription reaches the pharmacy, nothing is refunded
Regulatory note: the FDA issued a warning letter to Sprout Health Partners LLC dba Sprout Health in September 2025. We still list and link to Sprout Health; you should know the letter is on the public record before you decide.
Trellis Vitality
82/100Where the value is
- A single table shows one-, three- and six-month prices for both drugs, labeled as per-month prices: semaglutide $150, $140 and $133; tirzepatide $199, $189 and $179
- Same price at every dose, so your cost doesn't rise as you titrate up
- No membership fee, no consultation fee, and you can pause or cancel any time
The tradeoffs
- Its NAD+, glutathione, lipo-MIC and tesamorelin programs show only "starting at" prices with no plan table
- The refund policy says only that refunds are decided order by order
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.