Head-to-head · Cost-Efficiency Index
Sprout Health vs NewSelf
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Sprout Health
Price-first shoppers who want a fast, low-friction signup (often no labs or visit) at a verified pharmacy and don't need a named medical director.
Visit Sprout HealthNewSelf
Budget shoppers who want a verified all-50 program and one of the lowest disclosed tirzepatide prices in the value tier.
Visit NewSelfThe verdict
NewSelf takes it, leading the Cost-Efficiency Index 87 to 85. $100 semaglutide and $144 tirzepatide, nationwide and LegitScript-verified — near-identical value to the cheapest verified names, with the tirzepatide price a hair lower than most. Sprout Health still earns a B — Price-first shoppers who want a fast, low-friction signup (often no labs or visit) at a verified pharmacy and don't need a named medical director.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs NewSelf.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Sprout Health | NewSelf |
|---|---|---|
| Cost-Efficiency Index | 85/100 | 87/100 |
| Semaglutide / mo | $149/mo | $100/mo |
| Tirzepatide / mo | $199/mo | $144/mo |
| Semaglutide / yr (modeled) | $1,788 | $1,200 |
| Tirzepatide / yr (modeled) | $2,388 | $1,728 |
| Coverage | Most states | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #9 | #11 |
Sprout Health
85/100Where the value is
- Well-priced compounded — $149 semaglutide / $199 tirzepatide — with LegitScript certification behind it
- Low-friction intake: no labs and often no synchronous visit required
- Offers a brand-name Wegovy/Zepbound path alongside the compounded route
The tradeoffs
- No named medical director published, so clinical oversight is harder to attribute
- Availability is quiz-gated by state, so nationwide access isn't guaranteed until you qualify
Regulatory note: the FDA issued a warning letter to Sprout Health Partners LLC dba Sprout Health in September 2025. We still list and link to Sprout Health; you should know the letter is on the public record before you decide.
NewSelf
87/100Where the value is
- $100 semaglutide / $144 tirzepatide — one of the cheapest verified combined prices in the ranking
- Nationwide all-50 coverage with both molecules published up front
- LegitScript-certified pharmacy behind the low price
The tradeoffs
- Compounded only — no brand-name or oral option
- Newer consumer brand with a thin public track record
Regulatory note: the FDA issued a warning letter to NewSelf Limited dba NewSelf in February 2026. We still list and link to NewSelf; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.