Head-to-head · Cost-Efficiency Index
SkyRx vs WeightCare
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
SkyRx
Shoppers willing to commit and prepay a full year upfront in exchange for a lower blended monthly rate.
Visit SkyRxWeightCare
Cost-first shoppers who want a genuine month-to-month plan covering the full dose range, without a multi-month prepay commitment.
Visit WeightCareThe verdict
SkyRx takes it, leading the Cost-Efficiency Index 55 to 54. SkyRx is a telehealth platform selling compounded semaglutide (tirzepatide listed as 'coming soon') behind a headline $199/mo price that is actually a 12-month prepaid commitment rather than a monthly cash rate. WeightCare still earns a C — Cost-first shoppers who want a genuine month-to-month plan covering the full dose range, without a multi-month prepay commitment.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs SkyRx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | SkyRx | WeightCare |
|---|---|---|
| Cost-Efficiency Index | 55/100 | 54/100 |
| Semaglutide / mo | $199/mo (compounded) | $399/mo (all doses, compounded) |
| Tirzepatide / mo | Not disclosed | $499/mo (all doses, prepay plan, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $4,788 |
| Tirzepatide / yr (modeled) | — | $5,988 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #346 | #352 |
SkyRx
55/100Where the value is
- Simple, single headline price displayed on the weight-loss page
- Claims LegitScript certification
- Straightforward telehealth intake flow
The tradeoffs
- The '$199/mo' price is a 12-month prepay rate, not a cancel-anytime monthly price -- a major disclosure trap
- Tirzepatide not yet available ('coming soon'), so half the category is unpriced
WeightCare
54/100Where the value is
- True month-to-month plans exist with no prepay commitment, covering the full published dose range for both drugs
- PCAB-accredited, FDA-registered compounding pharmacies explicitly claimed (industry-recognized quality signal, though the specific pharmacy is not named)
- Cancellation requires only 7-day notice before renewal
The tradeoffs
- The cheapest advertised per-month prices ($215 sema, $275 tirz) require a full 6-month prepay ($1,290 / $1,650 up front) and cap you below the drug's top dose — going higher costs more via a separate High Dose plan
- No LegitScript certification found anywhere on the site
Regulatory note: the FDA issued a warning letter to Weightless Medical LLC dba WeightCare in February 2026. We still list and link to WeightCare; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.