Head-to-head · Cost-Efficiency Index
Signos vs Beluga Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Signos
Cost-first shoppers who want glucose-monitoring data paired with a GLP-1 prescription in one program, if a 3- or 6-month term is acceptable.
Visit SignosBeluga Health
Cost-first shoppers who want not applicable to consumers -- this is a B2B platform, not a GLP-1 provider a shopper can buy from directly.
Visit Beluga HealthThe verdict
Signos takes it, leading the Cost-Efficiency Index 44 to 43. Signos is a CGM-first metabolic-health company whose Signos+ plan genuinely bundles clinician-prescribed compounded semaglutide with its FDA-cleared continuous glucose monitor and coaching app. Beluga Health still earns a C — Cost-first shoppers who want not applicable to consumers -- this is a B2B platform, not a GLP-1 provider a shopper can buy from directly.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Signos.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Signos | Beluga Health |
|---|---|---|
| Cost-Efficiency Index | 44/100 | 43/100 |
| Semaglutide / mo | $199/mo (starting dose, bundle, plus a separate fee, compounded) | Not disclosed |
| Tirzepatide / mo | Not disclosed | Not disclosed |
| Semaglutide / yr (modeled) | $2,388 | — |
| Tirzepatide / yr (modeled) | — | — |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #486 | #490 |
Signos
44/100Where the value is
- Confirmed as a genuine GLP-1 prescriber, not CGM-only — the Signos+ plan bundles compounded semaglutide with the CGM, verified against the separate $127/mo CGM-only price
- Starting price of $199/month is stated to include both the medication program and the CGM hardware/app
- FDA-cleared CGM hardware paired with an AI-powered coaching app for ongoing glucose-guided tracking
The tradeoffs
- The headline $199/month is a 3- or 6-month PROGRAM rate, not a plain month-to-month subscription, and the page doesn't disclose what happens after the term ends
- Only semaglutide is shown in the bundled program; tirzepatide availability is not confirmed anywhere accessible
Beluga Health
43/100Where the value is
- Physician network led by a named, board-certified medical doctor licensed in all 50 states + DC
- Claims LegitScript-certified physician network
- Powers multiple consumer weight-loss brands, suggesting operational scale
The tradeoffs
- Not a consumer-facing product -- no way to buy semaglutide or tirzepatide directly from this site
- No pricing, dosing, or plan information published anywhere
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.