Head-to-head · Cost-Efficiency Index
ShedRx (Shed) vs YourEra
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
ShedRx (Shed)
People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.
Visit ShedRx (Shed)YourEra
Shoppers chasing the lowest sticker price who will verify what's actually billed after the first month.
Visit YourEraThe verdict
ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 62. The widest set of formats on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. YourEra still earns a C — Shoppers chasing the lowest sticker price who will verify what's actually billed after the first month.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx (Shed).
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | ShedRx (Shed) | YourEra |
|---|---|---|
| Cost-Efficiency Index | 87/100 | 62/100 |
| Semaglutide / mo | $199/mo ($159 on a 12-month plan) | $179/mo (all doses, month-to-month, compounded) |
| Tirzepatide / mo | $299/mo ($239 on a 12-month plan) | $259/mo (all doses, month-to-month, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $2,148 |
| Tirzepatide / yr (modeled) | $3,588 | $3,108 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Compounded only |
| Rank on the board | #3 | #152 |
ShedRx (Shed)
87/100Where the value is
- Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
- Brand Zepbound and Wegovy available alongside the compounded line
- Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee
The tradeoffs
- The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
YourEra
62/100Where the value is
- A 6-month prepay drops semaglutide to $99/month, among the lowest compounded-GLP-1 headline prices we track
- No membership-fee structure; the site markets "no hidden fees" and "Same price at every dose"
- Prescriptions are "issued only if deemed medically appropriate" after evaluation by licensed US clinicians, stated plainly
The tradeoffs
- The advertised $99/month requires a 6-month prepay — paying month to month costs $149 for the first month and $179/month after, nearly double the headline
- Tirzepatide's advertised $179 is a first-month intro, not a prepay rung: the page's own words are "Month-to-month intro. Then $259/mo." — so the two molecules' headline discounts work in two different ways on one page
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.