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Head-to-head · Cost-Efficiency Index

ShedRx (Shed) vs HealthRX

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #3

ShedRx (Shed)

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Visit ShedRx (Shed)
VS
Grade C · #38

HealthRX

Shoppers who want the whole term ladder published before intake and are reading it carefully enough to spot which rung the headline came from.

Visit HealthRX

The verdict

Winner · ShedRx (Shed)Grade B+ vs C

ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 74. The widest set of formats on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. HealthRX still earns a CShoppers who want the whole term ladder published before intake and are reading it carefully enough to spot which rung the headline came from.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx (Shed).

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
58

Price Transparency

74
94

Nationwide Access

92
86

Formulation Options

96
66

Clinical Oversight

84
79

Contract Flexibility

76
61

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecShedRx (Shed)HealthRX
Cost-Efficiency Index87/10074/100
Semaglutide / mo$199/mo ($159 on a 12-month plan)$190/mo (all doses, compounded)
Tirzepatide / mo$299/mo ($239 on a 12-month plan)$239/mo (all doses, compounded)
Semaglutide / yr (modeled)$2,388$2,280
Tirzepatide / yr (modeled)$3,588$2,868
CoverageAll 50 statesAll 50 states
Oral / sublingualYesNo
Brand-name accessYesCompounded only
Rank on the board#3#38

ShedRx (Shed)

87/100

Where the value is

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
  • Brand Zepbound and Wegovy available alongside the compounded line
  • Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee

The tradeoffs

  • The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
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Full ShedRx (Shed) review →

HealthRX

74/100

Where the value is

  • All 50 states, printed in the site's own header strip rather than left to the intake quiz
  • Specific, checkable LegitScript certificate number (50087439) rather than just a generic badge image
  • "Same price at every dose" policy avoids dose-based price creep

The tradeoffs

  • The advertised $99 and $179 are twelve-month prepay rungs — $1,188 and $2,148 up front. The standing month-to-month rates are $190 and $239, roughly double and a third higher
  • A second discount is stacked on the same headline: $99 semaglutide and $149 tirzepatide are also first-month intro rates on the monthly plan, so month two costs more than month one
Visit HealthRX

Full HealthRX review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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