Head-to-head · Cost-Efficiency Index
Shape Vantage vs Vyora Wellness
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Shape Vantage
Cost-first shoppers who want the lowest flat tirzepatide sticker price, for shoppers comfortable with a site that names no prescriber or pharmacy anywhere.
Visit Shape VantageVyora Wellness
Shoppers who want one flat price that never changes as their GLP-1 dose is titrated up.
Visit Vyora WellnessThe verdict
Shape Vantage and Vyora Wellness tie on the Cost-Efficiency Index at 52/100, so neither wins outright on the numbers. For most shoppers we'd start with Shape Vantage (ranked #392, a hair above #393) — Cost-first shoppers who want the lowest flat tirzepatide sticker price, for shoppers comfortable with a site that names no prescriber or pharmacy anywhere. But Vyora Wellness is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Shape Vantage.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Shape Vantage | Vyora Wellness |
|---|---|---|
| Cost-Efficiency Index | 52/100 | 52/100 |
| Semaglutide / mo | Not disclosed | $299/mo (all doses, compounded) |
| Tirzepatide / mo | $133/mo (3-month plan, compounded) | $399/mo |
| Semaglutide / yr (modeled) | — | $3,588 |
| Tirzepatide / yr (modeled) | $1,596 | $4,788 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #392 | #393 |
Shape Vantage
52/100Where the value is
- Lowest all-in sticker price of the 12 sites researched: $399 flat for a full 3-month tirzepatide program, no separate monthly billing
- Simple single-price structure with no dose-tier hedging or 'starting at' language
- At least one verifiable legal anchor: Terms page confirms the entity name and California governing law
The tradeoffs
- No physician, nurse practitioner, medical director, or individually named prescriber is disclosed anywhere on the site — every informational sub-page (about, how-it-works, FAQ, refund policy) 404s
- No compounding pharmacy is named, and the site never uses the words 'compounded,' 'prescription,' or 'pharmacy' — marketing language ('formulation kit,' 'product') reads closer to a supplement than a physician-prescribed medication
Vyora Wellness
52/100Where the value is
- Genuinely flat-rate pricing confirmed by its own FAQ — the monthly cost does not rise as the dose increases, unlike per-dose-tier competitors
- LegitScript certification verified to actually render on the live homepage (real badge and outbound verification link, not commented-out code)
- Coaching, nutritional guidance, and community access are bundled into the price at no extra charge
The tradeoffs
- Above-average flat pricing ($299-$399/mo) compared to per-dose-tier or 12-month-prepay competitors that can undercut it at low starting doses
- No specific compounding pharmacy is named — only a generic '503A certified pharmacies' claim
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.