Head-to-head · Cost-Efficiency Index
SexyMD vs Vyvron
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
SexyMD
Readers willing to commit 48 weeks up front, where the advertised figure is the one actually charged.
Visit SexyMDVyvron
Shoppers who want one all-in price with no membership fee and are comfortable budgeting for a four-week billing cycle.
Visit VyvronThe verdict
SexyMD and Vyvron tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers, so choose on fit. SexyMD: Readers willing to commit 48 weeks up front, where the advertised figure is the one actually charged. Vyvron: Shoppers who want one all-in price with no membership fee and are comfortable budgeting for a four-week billing cycle.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs SexyMD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | SexyMD | Vyvron |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $269/moOn the four-week plan (the site's "from $199" is the 48-week commitment rate) | $199Every 4 weeks (founding-member price; $249 after the founding spots fill, compounded) |
| Tirzepatide / mo | $369/moOn the four-week plan (the site's "from $299" is the 48-week commitment rate) | Not disclosed |
| Semaglutide / yr (modeled) | $3,49713 charges | $2,58713 charges |
| Tirzepatide / yr (modeled) | $4,79713 charges | — |
| Coverage | 47 states | 49 states (not Mississippi) |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #159 | #162 |
SexyMD
68/100Where the value is
- Publishes a full four-rung price table for each molecule on its product pages, before any intake
- States both pharmacy classes it uses and discloses that a prescription may be routed to, and transferred between, any pharmacy in that network
- Names the professional entities its prescribers work through, rather than referring only to licensed providers
The tradeoffs
- Every headline on the site quotes the 48-week rate: "from $199 per month" against a four-week price of $269, and "from $299" against $369, with an asterisk that resolves to no footnote
- The same footer block says both "available in all 50 states" and "available in all states except Arkansas, Mississippi, and New Jersey", on all eleven pages
Vyvron
68/100Where the value is
- One price covers the provider evaluation, the medication if prescribed, ongoing check-ins and shipping, with no membership fee
- No long-term contract and no cancellation fee; you cancel by email or in the patient portal
- Full refund if a provider doesn't approve you
The tradeoffs
- Billing is every four weeks, not monthly, so a year at $199 is 13 charges and $2,587
- The pages don't say whether tirzepatide costs the same as semaglutide; the provider chooses which one you get
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.