Head-to-head · Cost-Efficiency Index
Sesame Care vs Sprout Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Sesame Care
People who specifically want FDA-approved brand-name medication (including the Wegovy pill or oral Rybelsus) from an established, verified marketplace and will budget for a two-part cost.
Visit Sesame CareSprout Health
Price-first shoppers who want a fast, low-friction signup (often no labs or visit) at a verified pharmacy and don't need a named medical director.
Visit Sprout HealthThe verdict
Sesame Care takes it, leading the Cost-Efficiency Index 86 to 85. The widest real brand-name GLP-1 access in the ranking — a LegitScript- and BBB-recognized national marketplace running since 2018 that dispenses FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro and Rybelsus, not compounded copies. Sprout Health still earns a B — Price-first shoppers who want a fast, low-friction signup (often no labs or visit) at a verified pharmacy and don't need a named medical director.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Sesame Care.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Sesame Care | Sprout Health |
|---|---|---|
| Cost-Efficiency Index | 86/100 | 85/100 |
| Semaglutide / mo | $149/mo medication + $59/mo care subscription (that rate needs a 12-month commitment) | $149/mo |
| Tirzepatide / mo | Brand (Zepbound) | $199/mo |
| Semaglutide / yr (modeled) | — | $1,788 |
| Tirzepatide / yr (modeled) | — | $2,388 |
| Coverage | Nationwide | Most states |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Yes |
| Rank here | #7 | #10 |
Sesame Care
86/100Where the value is
- Widest brand-name formulary we list — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and oral Rybelsus, all FDA-approved rather than compounded
- Established national marketplace operating since 2018, with LegitScript certification and BBB recognition
- Wegovy pill starts around $149/mo, and oral routes are available for the needle-averse
The tradeoffs
- Two-part cost — $149/mo medication plus a separate care subscription from $59/mo, so the all-in floor is about $208/mo, and the $59 rate itself requires a 12-month commitment
- A generalist telehealth marketplace, not a dedicated GLP-1 program
Sprout Health
85/100Where the value is
- Well-priced compounded — $149 semaglutide / $199 tirzepatide — with LegitScript certification behind it
- Low-friction intake: no labs and often no synchronous visit required
- Offers a brand-name Wegovy/Zepbound path alongside the compounded route
The tradeoffs
- No named medical director published, so clinical oversight is harder to attribute
- Availability is quiz-gated by state, so nationwide access isn't guaranteed until you qualify
Regulatory note: the FDA issued a warning letter to Sprout Health Partners LLC dba Sprout Health in September 2025. We still list and link to Sprout Health; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.