Head-to-head · Cost-Efficiency Index
Sesame Care vs Effecty
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Sesame Care
People who specifically want FDA-approved brand-name medication (including the Wegovy pill or oral Rybelsus) from an established, verified marketplace and will budget for a two-part cost.
Visit Sesame CareEffecty
People who want competitive compounded pricing but also the option to step up to brand-name, verified and nationwide.
Visit EffectyThe verdict
Sesame Care and Effecty tie on the Cost-Efficiency Index at 86/100, so neither wins outright on the numbers. For most shoppers we'd start with Sesame Care (ranked #7, a hair above #14) — People who specifically want FDA-approved brand-name medication (including the Wegovy pill or oral Rybelsus) from an established, verified marketplace and will budget for a two-part cost. But Effecty is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Sesame Care.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Sesame Care | Effecty |
|---|---|---|
| Cost-Efficiency Index | 86/100 | 86/100 |
| Semaglutide / mo | $149/mo medication + $59/mo care subscription (that rate needs a 12-month commitment) | $160/mo |
| Tirzepatide / mo | Brand (Zepbound) | $240/mo |
| Semaglutide / yr (modeled) | — | $1,920 |
| Tirzepatide / yr (modeled) | — | $2,880 |
| Coverage | Nationwide | All 50 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Yes |
| Rank here | #7 | #14 |
Sesame Care
86/100Where the value is
- Widest brand-name formulary we list — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and oral Rybelsus, all FDA-approved rather than compounded
- Established national marketplace operating since 2018, with LegitScript certification and BBB recognition
- Wegovy pill starts around $149/mo, and oral routes are available for the needle-averse
The tradeoffs
- Two-part cost — $149/mo medication plus a separate care subscription from $59/mo, so the all-in floor is about $208/mo, and the $59 rate itself requires a 12-month commitment
- A generalist telehealth marketplace, not a dedicated GLP-1 program
Effecty
86/100Where the value is
- Both molecules disclosed at competitive prices with all-50 access
- Offers FDA-approved brand-name access alongside compounded
- LegitScript-certified pharmacy
The tradeoffs
- Per-month cost is mid-market, not budget-tier
- No oral/sublingual option
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.