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Head-to-head · Cost-Efficiency Index

Semaglutide Online vs VitaStir

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #200

Semaglutide Online

Shoppers who want one all-inclusive compounded price with no add-on provider fee, and don't mind the site's own numbers not always agreeing.

Visit Semaglutide Online
VS
Grade C · #201

VitaStir

Cost-first shoppers who want michigan residents who want in-person clinic visits alongside an at-home GLP-1 option.

Visit VitaStir

The verdict

Too close to callGrade C vs C

Semaglutide Online and VitaStir tie on the Cost-Efficiency Index at 63/100, so neither wins outright on the numbers. For most shoppers we'd start with Semaglutide Online (ranked #200, a hair above #201) — Shoppers who want one all-inclusive compounded price with no add-on provider fee, and don't mind the site's own numbers not always agreeing. But VitaStir is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Semaglutide Online.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
74

Price Transparency

54
78

Nationwide Access

86
24

Formulation Options

64
66

Clinical Oversight

81
79

Contract Flexibility

55
49

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecSemaglutide OnlineVitaStir
Cost-Efficiency Index63/10063/100
Semaglutide / moNot disclosed$125/mo (compounded)
Tirzepatide / moNot disclosed$145/mo (compounded)
Semaglutide / yr (modeled)$1,500
Tirzepatide / yr (modeled)$1,740
CoverageAll 50 statesCoverage not published
Oral / sublingualYesNo
Brand-name accessYesCompounded only
Rank here#200#201

Semaglutide Online

63/100

Where the value is

  • Compounded tier is genuinely all-inclusive — no separate $44/mo provider subscription, unlike its own branded-drug track
  • Offers 0% interest financing plans (12 or 24 months) for those who want to spread the cost
  • No long-term contract — site states you can cancel anytime

The tradeoffs

  • The compounded semaglutide price is internally inconsistent on the site's own product page — $179/mo appears in one place, $199/mo (all-inclusive) in another, with no reconciliation
  • Brand-name options carry a headline medication price that excludes a mandatory separate $44/mo provider subscription, understating the real all-in cost by nearly 20%
Visit Semaglutide Online

Full Semaglutide Online review →

VitaStir

63/100

Where the value is

  • Real physical clinic locations with in-person options, not purely virtual
  • Displays a LegitScript approved badge and states PCAB pharmacy licensing
  • Low headline sale prices on both semaglutide and tirzepatide homekits

The tradeoffs

  • Physical footprint is Michigan-only -- not a true nationwide option despite an online-order path
  • Large 'reduced from' discounts (64-79% off) with no expiration date look like a permanent pricing anchor, not a real promo
Visit VitaStir

Full VitaStir review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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