Head-to-head · Cost-Efficiency Index
RxPepsDirect vs YourHealthRx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
RxPepsDirect
Cost-first shoppers who want the all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.
Visit RxPepsDirectYourHealthRx
Cost-first shoppers who want science-forward GLP-1 and peptide care, flat-rate dosing, built-in follow-up.
Visit YourHealthRxThe verdict
RxPepsDirect and YourHealthRx tie on the Cost-Efficiency Index at 60/100, so neither wins outright on the numbers. For most shoppers we'd start with RxPepsDirect (ranked #256, a hair above #260) — Cost-first shoppers who want the all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states. But YourHealthRx is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs RxPepsDirect.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | RxPepsDirect | YourHealthRx |
|---|---|---|
| Cost-Efficiency Index | 60/100 | 60/100 |
| Semaglutide / mo | $79/mo (starting dose, visit fee and shipping included, compounded) | $170/mo (compounded) |
| Tirzepatide / mo | $99/mo (starting dose, visit fee and shipping included, compounded) | $210/mo (compounded) |
| Semaglutide / yr (modeled) | $948 | $2,040 |
| Tirzepatide / yr (modeled) | $1,188 | $2,520 |
| Coverage | 28 states | All 50 states |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #256 | #260 |
RxPepsDirect
60/100Where the value is
- Every component of the price is published on the site — the vial tiers, the flat visit charge and the flat overnight delivery — so the all-in monthly cost can be worked out before ordering
- No subscription and no commitment: you pay per order, and one visit charge covers up to three peptides on the same prescription
- Real 503A telehealth Rx — licensed NP/PA prescribers under medical director Dr. Jonathan Snipes (NPI 1821250077), dispensed by Optimal Balance Pharmacy, Texas Ranking #34829
The tradeoffs
- The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once
- Higher doses need more than one vial a month and the site publishes no price for the dose you titrate up to, so the figure above is a floor
YourHealthRx
60/100Where the value is
- Available in all 50 states and DC through a multi-state (IMLC) licensed clinician network
- Compounded semaglutide and tirzepatide in two formats - weekly injectable (with B12) or daily oral dissolving tablet
- Flat subscription price that doesn't change as your dose increases (no titration penalty)
The tradeoffs
- Eligibility and prescribing run through partner clinical workflows - YourHealthRx is the platform, not the prescriber or pharmacy
- Compounded medications are not FDA-approved - not brand Wegovy, Ozempic, Zepbound, or Mounjaro
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.