Head-to-head · Cost-Efficiency Index
Rx.com vs HealthRX
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Rx.com
Someone who will judge it by the plan card rather than the banner, and who values no auto-renewal and a named pharmacy over the lowest sticker.
Visit Rx.comHealthRX
Shoppers who want the whole term ladder published before intake and are reading it carefully enough to spot which rung the headline came from.
Visit HealthRXThe verdict
Rx.com takes it, leading the Cost-Efficiency Index 77 to 74. Prints "No automatic renewals" on the plan card and names the pharmacy that dispenses, with a street address — then advertises another drug's prepay rate. HealthRX still earns a C — Shoppers who want the whole term ladder published before intake and are reading it carefully enough to spot which rung the headline came from.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Rx.com.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Rx.com | HealthRX |
|---|---|---|
| Cost-Efficiency Index | 77/100 | 74/100 |
| Semaglutide / mo | $175/mo month-to-month; $165 on three months and $146 on six | $190/mo (all doses, compounded) |
| Tirzepatide / mo | $285/mo month-to-month; $265 on three months and $259 on six | $239/mo (all doses, compounded) |
| Semaglutide / yr (modeled) | $2,100 | $2,280 |
| Tirzepatide / yr (modeled) | $3,420 | $2,868 |
| Coverage | 49 states on its plan page; its own banner says all 50 | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #45 | #46 |
Rx.com
77/100Where the value is
- "No automatic renewals" is printed under the plan card itself rather than buried in the terms
- Names Manifest Pharmacy in Greer, South Carolina with a full street address, and MD Integrations as the provider network, on the same page as the price
- One flat price at every dose from 2.5 mg to 15 mg, with the provider visit, injection supplies and cold shipping stated as included
The tradeoffs
- The advertised "$146/mo FOR LIFE" is a six-month prepay on semaglutide; month-to-month tirzepatide is $285
- The plan page says 49 states served while the banner on the same site says all 50
HealthRX
74/100Where the value is
- All 50 states, printed in the site's own header strip rather than left to the intake quiz
- Specific, checkable LegitScript certificate number (50087439) rather than just a generic badge image
- "Same price at every dose" policy avoids dose-based price creep
The tradeoffs
- The advertised $99 and $179 are twelve-month prepay rungs — $1,188 and $2,148 up front. The standing month-to-month rates are $190 and $239, roughly double and a third higher
- A second discount is stacked on the same headline: $99 semaglutide and $149 tirzepatide are also first-month intro rates on the monthly plan, so month two costs more than month one
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.