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WeighLab

Rila vs PlushCare

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Rila

Provider comparison

Patients comparing injection and tablet options who can obtain a drug-specific quote and clarify the six-month commitment before enrolling.

Semaglutide / month
Shared injectable floor $198/mo with six-month commitment; semaglutide-specific total not disclosed
Tirzepatide / month
Shared injectable floor $198/mo with six-month commitment; tirzepatide-specific total not disclosed
Index 62/100 · Grade CChecked October 2026
Check Rila pricing Read review

PlushCare

Provider comparison

Patients who want a real board-certified physician managing GLP-1s alongside general primary care, and are prepared to navigate insurance or a manufacturer cash-pay program rather than a single flat price.

Semaglutide / month
$499/moBrand Wegovy through NovoCare Pharmacy, plus a separate fee
Tirzepatide / month
$299/mo2.5 mg brand Zepbound vial through LillyDirect; $399 at 5 mg, $449 at 7.5 mg and up, plus a separate fee
Index 61/100 · Grade CChecked October 2026
Check PlushCare pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Rila has the higher Cost-Efficiency Index: 62/100 versus 61/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Rila
All 50 states and Washington, D.C.; treatment and consultation requirements vary
PlushCare
All 50 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Rila

PlushCare

Semaglutide / month
Rila: Shared injectable floor $198/mo with six-month commitment; semaglutide-specific total not disclosed
PlushCare: $499/moBrand Wegovy through NovoCare Pharmacy, plus a separate fee
Tirzepatide / month
Rila: Shared injectable floor $198/mo with six-month commitment; tirzepatide-specific total not disclosed
PlushCare: $299/mo2.5 mg brand Zepbound vial through LillyDirect; $399 at 5 mg, $449 at 7.5 mg and up, plus a separate fee
Semaglutide / year (modeled)
Rila: —
PlushCare: $6,228Includes $19.99/mo membership
Tirzepatide / year (modeled)
Rila: —
PlushCare: $3,828Includes $19.99/mo membership
State availability
Rila: All 50 states and Washington, D.C.; treatment and consultation requirements vary
PlushCare: All 50 states
Oral / sublingual option listed
Rila: Yes
PlushCare: Not listed
Brand-name access listed
Rila: Not confirmed
PlushCare: Yes
Provider facts checked
Rila: October 2026
PlushCare: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Rila

Patients comparing injection and tablet options who can obtain a drug-specific quote and clarify the six-month commitment before enrolling.

Reasons to consider it

  • Offers compounded injections and dissolving tablets for both medications
  • Names DrTelX and EPIQ Scripts, Foothills Professional Pharmacy and Emerald Pharmacy
  • Terms state service in all 50 states and Washington, D.C., subject to eligibility

What to weigh up

  • The $198 injection and $217 tablet floors are shared across drugs and require a six-month commitment
  • A full semaglutide- or tirzepatide-specific plan total is not published
  • Refund policy describes monthly automatic renewal; confirm obligations under the advertised commitment
Check Rila pricing Read the full Rila review

PlushCare

Patients who want a real board-certified physician managing GLP-1s alongside general primary care, and are prepared to navigate insurance or a manufacturer cash-pay program rather than a single flat price.

Reasons to consider it

  • Board-certified physicians (not NP-only) available in all 50 states for general virtual primary care
  • Lists the Zepbound self-pay prices by dose on its own page: vials at $299, $399 and $449 a month, pens at $650
  • Owned by Transcarent, a venture-backed platform with a named, traceable corporate lineage

What to weigh up

  • Compounded semaglutide ($149 at 0.25 mg, $299 above) is offered only while the brand drug is on FDA's shortage list, and compounded options only in 40 states plus DC
  • A $19.99/mo membership (first month free) and, without insurance, a $129 visit come on top of the medication price
  • The Wegovy page still quotes a $199 first-months price 'valid through March 2026', a date that has passed; its own headline says from $499
Check PlushCare pricing Read the full PlushCare review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

RilaPlushCare
Normalized Cost/Month
Rila:
45/100
PlushCare:
27/100
Price Transparency
Rila:
60/100
PlushCare:
64/100
Nationwide Access
Rila:
86/100
PlushCare:
86/100
Formulation Options
Rila:
77/100
PlushCare:
79/100
Clinical Oversight
Rila:
65/100
PlushCare:
82/100
Contract Flexibility
Rila:
43/100
PlushCare:
41/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.