Head-to-head · Cost-Efficiency Index
Rex MD vs Mint Med
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Rex MD
Cost-first shoppers who want men wanting brand-name Wegovy/Zepbound access through a manufacturer direct-pay bridge, not compounded medication.
Visit Rex MDMint Med
Cost-first shoppers who want the simplicity of one flat price across both semaglutide and tirzepatide, in the 35 states it explicitly serves.
Visit Mint MedThe verdict
Rex MD takes it, leading the Cost-Efficiency Index 56 to 55. Rex MD (a LifeMD brand, historically known for ED telehealth) also runs a real weight-management program, but it is a referral model rather than a compounder: a $75/month Rex MD program fee covers consultation, coaching and labs. Mint Med still earns a C — Cost-first shoppers who want the simplicity of one flat price across both semaglutide and tirzepatide, in the 35 states it explicitly serves.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Rex MD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Rex MD | Mint Med |
|---|---|---|
| Cost-Efficiency Index | 56/100 | 55/100 |
| Semaglutide / mo | $574/mo (all doses, plus a separate fee, brand-name) | Not disclosed |
| Tirzepatide / mo | $424/mo (brand Zepbound, plus a separate fee) | Not disclosed |
| Semaglutide / yr (modeled) | $6,888 | — |
| Tirzepatide / yr (modeled) | $5,088 | — |
| Coverage | All 50 states | 36 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #331 | #334 |
Rex MD
56/100Where the value is
- Genuine FDA-approved brand-name medication (Wegovy, Zepbound, Saxenda) rather than compounded — a different, more regulated tier than most of this list
- Named medical leadership (Dr. Anthony Puopolo, M.D., Rex MD Affiliated Medical Group) and a LegitScript Certified badge
- Backed by publicly known parent LifeMD, with an established telehealth track record
The tradeoffs
- The headline $75 is NOT the medication cost — Wegovy runs an additional $499/mo (any dose) and Zepbound vials an additional $349/mo, both billed separately by the manufacturer, not Rex MD
- All-in realistic cost is roughly $424-$574/month, far above what a '$75' or even a '$349' headline implies depending on which landing page you see
Mint Med
55/100Where the value is
- Single, simple flat price ($159/mo) applies to any dose of either drug — no dose-escalation surcharge structure to parse
- No membership fee ('NO memberships!') and cancellation requires only 48 business hours notice
- Explicit immediate-refund commitment if a clinical reviewer finds the applicant ineligible
The tradeoffs
- Payment is collected upfront, before a clinician has reviewed and approved the prescription — patients front the money before knowing they'll be approved
- Only 35 states are served by name — notably absent are several populous states not on the published list, so most shoppers should check it before assuming eligibility
Regulatory note: the FDA issued a warning letter to Glow Medispa, LLC dba Mint Med in June 2026. We still list and link to Mint Med; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.