Head-to-head · Cost-Efficiency Index
Renlo Health vs TrimRx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Renlo Health
Someone who wants a flat monthly bill that will not step up, with a refund route if it does not work.
Visit Renlo HealthTrimRx
Shoppers who want one monthly package that covers the visit, the medication and shipping, and who will confirm the renewal price at checkout.
Visit TrimRxThe verdict
Renlo Health takes it, leading the Cost-Efficiency Index 78 to 77. A price lock, a named prescriber and a named pharmacy — and a headline that is the actual monthly rate rather than a prepay divided down. TrimRx still earns a C — Shoppers who want one monthly package that covers the visit, the medication and shipping, and who will confirm the renewal price at checkout.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Renlo Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Renlo Health | TrimRx |
|---|---|---|
| Cost-Efficiency Index | 78/100 | 77/100 |
| Semaglutide / mo | $199/moBilled monthly at every dose | $299/moMonth-to-month refill price; first month $199, compounded |
| Tirzepatide / mo | $269/moBilled monthly at every dose | $399/moMonth-to-month refill price; first month $349, compounded |
| Semaglutide / yr (modeled) | $2,388 | $3,588 |
| Tirzepatide / yr (modeled) | $3,228 | $4,788 |
| Coverage | Not disclosed | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #49 | #56 |
Renlo Health
78/100Where the value is
- The headline is the real month-to-month rate — no prepay division and no commitment behind an asterisk
- Names the prescribing physician, Dr. Sean Arora, MD, and the dispensing pharmacy, VialsRX
- Same price at every dose with a price-lock badge, so titrating up never moves the bill
The tradeoffs
- A struck-through $299 sits beside the price with no published basis — Renlo never says what it was, when it applied or to whom
- That strikethrough comes from a stylesheet rule rather than a struck-out element, so a markup-level check would report the page clean
TrimRx
77/100Where the value is
- Each monthly package includes the telehealth consultation, the prescription, the medication and shipping, with no separate membership fee listed
- The homepage promises the price stays the same as your dose goes up, and offers to keep your current dose if you switch from another program
- Serves all 50 states, and the terms say so plainly
The tradeoffs
- The homepage says "Starting at $179" and "$259", but the terms list $199 and $349 for the first month and $299 and $399 for each follow-up month, so confirm which price applies to you before paying
- Once your prescription is sent to the pharmacy that month's order can't be refunded; refunds on prepaid multi-month plans must be requested within 28 days of payment
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.