Head-to-head · Cost-Efficiency Index
PrescribedRX vs MyStart Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
PrescribedRX
Shoppers who want flat, dose-independent pricing and are also interested in bundling TRT or hair loss treatment on the same platform.
Visit PrescribedRXMyStart Health
Shoppers who want a single flat all-inclusive monthly price and don't need semaglutide vs. tirzepatide broken out separately.
Visit MyStart HealthThe verdict
PrescribedRX takes it, leading the Cost-Efficiency Index 50 to 49. PrescribedRX is a multi-category telehealth platform offering compounded injectable semaglutide and tirzepatide for weight loss alongside TRT, hair loss, and sexual health treatments. MyStart Health still earns a C — Shoppers who want a single flat all-inclusive monthly price and don't need semaglutide vs. tirzepatide broken out separately.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs PrescribedRX.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | PrescribedRX | MyStart Health |
|---|---|---|
| Cost-Efficiency Index | 50/100 | 49/100 |
| Semaglutide / mo | $189/mo (all doses, prepay plan, compounded) | $299/mo (compounded) |
| Tirzepatide / mo | $276/mo (all doses, prepay plan, compounded) | Not disclosed |
| Semaglutide / yr (modeled) | $2,268 | $3,588 |
| Tirzepatide / yr (modeled) | $3,312 | — |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #412 | #418 |
PrescribedRX
50/100Where the value is
- Dose-flat pricing -- cost doesn't increase as you titrate up
- Both compounded semaglutide and tirzepatide offered
- LegitScript badge displayed
The tradeoffs
- 3-month tirzepatide 'starting at' price is a $697 upfront prepay trap, not the real monthly rate
- Confusing bundle pricing where the 'special offer' is actually pricier than the plain monthly plan
MyStart Health
49/100Where the value is
- Genuinely all-inclusive stated price: physician evaluations, unlimited follow-ups, bloodwork, and shipping are explicitly bundled into the $299 figure with 'no hidden fees'
- Price-lock guarantee explicitly covers dose increases — the FAQ states the price won't rise 'even if your dosage increases'
- Named Chief Medical Advisor (Dr. Ritu Chopra, Beverly Hills MD)
The tradeoffs
- Does not publish separate pricing for semaglutide vs. tirzepatide — $299 is a single blended program price, so it's unclear which drug (or whether both) that figure actually buys
- A sitewide 'Lifetime 25% Off' promo banner is not reconciled against the stated '$299/month excluding any discounts' base price or the price-lock guarantee's 'excluding our first-time discount' exception — genuinely ambiguous what a patient ends up paying long-term
Regulatory note: the FDA issued a warning letter to Matthew Stern, CEO MyStart Health LLC. in September 2025. We still list and link to MyStart Health; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.