Head-to-head · Cost-Efficiency Index
Pomegranate Health vs Ryze Rx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Pomegranate Health
Cost-first shoppers who want a no-membership compounded GLP-1 whose semaglutide price is published on the product page itself.
Visit Pomegranate HealthRyze Rx
Cost-first shoppers who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.
Visit Ryze RxThe verdict
Pomegranate Health and Ryze Rx tie on the Cost-Efficiency Index at 54/100, so neither wins outright on the numbers. For most shoppers we'd start with Pomegranate Health (ranked #362, a hair above #364) — Cost-first shoppers who want a no-membership compounded GLP-1 whose semaglutide price is published on the product page itself. But Ryze Rx is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Pomegranate Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Pomegranate Health | Ryze Rx |
|---|---|---|
| Cost-Efficiency Index | 54/100 | 54/100 |
| Semaglutide / mo | $119/mo (starting price, compounded) | $199/mo (starting dose, 3 month plan, compounded) |
| Tirzepatide / mo | $149/mo (Starter tier, compounded) | $199/mo (starting dose, 3 month plan, compounded) |
| Semaglutide / yr (modeled) | $1,428 | $2,388 |
| Tirzepatide / yr (modeled) | $1,788 | $2,388 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #362 | #364 |
Pomegranate Health
54/100Where the value is
- No membership and no consultation fee — the site states 'No Membership required' and 'Transparent pricing, no hidden fees'
- The semaglutide price sits in the product page's own static HTML, so it can be read before any intake
- Shipping is included: 'shipped discreetly to your door at no extra cost'
The tradeoffs
- The tirzepatide price is not on the public site at all — it exists only inside the in-app pricing portal, and there is no standalone tirzepatide product page to read it from
- Both published figures are floors, a 'Starts @' and a Starter tier, and no price is published for the dose you titrate up to
Ryze Rx
54/100Where the value is
- Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
- Physician consultation, ongoing clinical support and discreet shipping included with each prescription
- Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)
The tradeoffs
- Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
- Pharmacy partners not named - only 'US-licensed compounding pharmacies'
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.