Head-to-head · Cost-Efficiency Index
PlexusDx vs NP2GO
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
PlexusDx
Shoppers who want a published starting price with an oral semaglutide option, all 50 states.
Visit PlexusDxNP2GO
Shoppers inside its 40 served states who want both molecules disclosed and will vet the pharmacy themselves.
Visit NP2GOThe verdict
PlexusDx takes it, leading the Cost-Efficiency Index 82 to 79. PlexusDx is a nationwide compounded-GLP-1 telehealth platform offering both semaglutide (injection or oral tablet) and tirzepatide from published starting prices, LegitScript certified. NP2GO still earns a C — Shoppers inside its 40 served states who want both molecules disclosed and will vet the pharmacy themselves.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs PlexusDx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | PlexusDx | NP2GO |
|---|---|---|
| Cost-Efficiency Index | 82/100 | 79/100 |
| Semaglutide / mo | $149/mo (all doses, compounded) | $150/mo |
| Tirzepatide / mo | $249/mo (all doses, compounded) | $250/mo |
| Semaglutide / yr (modeled) | $1,788 | $1,800 |
| Tirzepatide / yr (modeled) | $2,988 | $3,000 |
| Coverage | All 50 states | AK, AZ, AR, CA, CO, CT, DE, DC, FL, HI, ID, IL, IA, KS, KY, ME, MD, MA, MI, MN, MT, NE, NV, NH, NJ, NM, NY, ND, OK, OR, PA, RI, SD, TX, UT, VT, VA, WA, WV, WY |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #26 | #33 |
PlexusDx
82/100Where the value is
- LegitScript Certified, stated directly on the homepage
- Both injection and oral tablet formats for semaglutide from the same starting price
- All 50 states served
The tradeoffs
- 'Starts at' pricing — the page does not disclose what higher doses cost, so $149/$249 is a floor, not what most patients settling into a maintenance dose will pay
- No named prescriber, medical director, or specific compounding pharmacy
NP2GO
79/100Where the value is
- Both molecules disclosed — $150 semaglutide / $250 tirzepatide — for straightforward cost modeling
- Broad 40-state footprint — wider than most non-nationwide operators
- Flat, predictable pricing
The tradeoffs
- 40 states, not all 50 — a coverage gamble that dents its access score
- Not LegitScript-certified — oversight harder to verify
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.