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Head-to-head · Cost-Efficiency Index

Peter MD vs Amble

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Grade C · #54

Peter MD

Someone who wants a single telehealth account to also cover TRT, hair loss, ED or NAD+ alongside a GLP-1 script, and who will read past the first-month price before budgeting the ongoing cost.

Visit Peter MD
VS
Better valueGrade C · #56

Amble

Cost-first shoppers who want a single flat rate across semaglutide and tirzepatide, if a 12-month prepay is acceptable.

Visit Amble

The verdict

Winner · AmbleGrade C vs C

Amble takes it, leading the Cost-Efficiency Index 74 to 72. Amble is a managed-services telehealth platform (by its own terms, not itself a medical facility or pharmacy) selling compounded semaglutide and tirzepatide at IDENTICAL prices on a commitment-length pricing table: $179/mo with no commitment. Peter MD still earns a CSomeone who wants a single telehealth account to also cover TRT, hair loss, ED or NAD+ alongside a GLP-1 script, and who will read past the first-month price before budgeting the ongoing cost.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Amble.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

65
62

Price Transparency

74
94

Nationwide Access

68
86

Formulation Options

92
66

Clinical Oversight

75
79

Contract Flexibility

62
47

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecPeter MDAmble
Cost-Efficiency Index72/10074/100
Semaglutide / mo$149/mo first-time (Level 1), $139/mo returning (Level 2)$179/mo (all doses, compounded)
Tirzepatide / mo$149 first month, then $249/mo billed quarterly$179/mo (all doses, compounded)
Semaglutide / yr (modeled)$1,788$2,148
Tirzepatide / yr (modeled)$2,988$2,148
CoverageVaries by treatment — excluded in several states (marketing pages list AL/ID; the affiliate program's own disclosure is wider)All 50 states
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank here#54#56

Peter MD

72/100

Where the value is

  • Broadest cross-category catalog in this ranking under one account: TRT, ED, non-GLP-1 weight loss, GLP-1 (semaglutide/tirzepatide), men's hair loss and NAD+, plus sermorelin
  • Physician-prescribed, nationwide telehealth brand operating since 2021 (Miami, FL HQ)
  • Sermorelin ($585 for a 12-week supply, ~$195/mo) and NAD+ ($369 for an 8-10 week supply, ~$147-184/mo) sit in the same catalog as the GLP-1 line for anyone consolidating multiple scripts

The tradeoffs

  • Tirzepatide's $149 first-month rate steps up to $249/mo billed quarterly — the number that matters for budgeting is the renewal price, not the headline
  • Semaglutide pricing depends on tier: $149/mo first-time (Level 1) vs $139/mo returning (Level 2), with different total costs ($447 vs $834) over different supply windows, so the all-in cost is not a single number
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Full Peter MD review →

Amble

74/100

Where the value is

  • No difference in price between semaglutide and tirzepatide — genuinely one pricing table for both
  • True no-commitment option exists ($179/mo, pay as you go) alongside the prepay tiers
  • All 50 states, with only 5 requiring a live video visit instead of async intake

The tradeoffs

  • The advertised low-end price ($135-$160/mo) is not a monthly bill — it's a one-time lump-sum prepay for the whole 3/6/12-month term, stated explicitly on the page
  • No named medical director, prescriber, or compounding pharmacy anywhere on the site
Visit Amble

Full Amble review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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