Pepti vs He & She MD

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Pepti

Provider comparison

Shoppers who want to see the price of every dose step before they start, with no membership fee on top.

Semaglutide / month: $99/mo0.25 mg starting dose, compounded; $109–$199 at higher doses
Tirzepatide / month: $159/mo2.5 mg starting dose, compounded; $179–$319 at higher doses

Index 80/100 · Grade B−Checked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Pepti pricing Read review

He & She MD

Provider comparison

Readers comparing monthly treatment against prepaid terms who will resolve conflicting product-page prices before paying.

Semaglutide / month: $199/moMonth to month, compounded; every lower rate is a prepaid term
Tirzepatide / month: $299/moMonth to month, compounded; every lower rate is a prepaid term

Index 79/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check He & She MD pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Pepti has the higher Cost-Efficiency Index: 80/100 versus 79/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Pepti: All 50 states
He & She MD: 49 states, excluding Louisiana (GLP-1)

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Pepti

He & She MD

Semaglutide / month: Pepti: $99/mo0.25 mg starting dose, compounded; $109–$199 at higher doses; He & She MD: $199/moMonth to month, compounded; every lower rate is a prepaid term

Tirzepatide / month: Pepti: $159/mo2.5 mg starting dose, compounded; $179–$319 at higher doses; He & She MD: $299/moMonth to month, compounded; every lower rate is a prepaid term

Semaglutide / year (modeled): Pepti: $1,28713 charges; He & She MD: $2,388

Tirzepatide / year (modeled): Pepti: $2,06713 charges; He & She MD: $3,588

State availability: Pepti: All 50 states; He & She MD: 49 states, excluding Louisiana (GLP-1)

Oral / sublingual option listed: Pepti: Not listed; He & She MD: Yes

Brand-name access listed: Pepti: Not confirmed; He & She MD: Yes

Provider facts checked: Pepti: October 2026; He & She MD: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Pepti

Shoppers who want to see the price of every dose step before they start, with no membership fee on top.

Reasons to consider it

Every dose has its own published price: semaglutide runs $99 to $199 and tirzepatide $159 to $319
No membership fee; the medication price includes physician review, dose adjustments and free shipping
Names a reviewing physician and a dispensing pharmacy, Olympia Pharmacy

What to weigh up

The price rises as your dose goes up, so the $99 starting figure covers only the first step of semaglutide
It bills every 28 days rather than monthly, which adds up to 13 charges a year
You pay at checkout before a provider reviews your intake; you're refunded if you're declined

Compounded drugs are not FDA-approved. Understand the medication options.

Check Pepti pricing Read the full Pepti review

He & She MD

Readers comparing monthly treatment against prepaid terms who will resolve conflicting product-page prices before paying.

Reasons to consider it

Offers compounded semaglutide and tirzepatide injections and oral options, plus branded GLP-1 prescribing
Names Dr. Ozita Cooper as CMO, Wasef Health as the provider group, and two dispensing partners: Jungle Jim's Pharmacy and GoGoMeds
Publishes monthly, quarterly, six-month and annual plans

What to weigh up

The plans page lists $199 semaglutide and $299 tirzepatide monthly, but the individual injection pages list $249 and $339 for one month; confirm the actual bill
Quarterly, six-month and annual prices require the whole term paid upfront; six-month promotional terms may renew higher
The FAQ says Jungle Jim's cannot dispense sterile compounds and lists state exclusions; ask which partner fills your injectable prescription

Compounded drugs are not FDA-approved. Understand the medication options.

Check He & She MD pricing Read the full He & She MD review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

PeptiHe & She MD

Normalized Cost/Month: Pepti:
81/100; He & She MD:
78/100

Price Transparency: Pepti:
84/100; He & She MD:
97/100

Nationwide Access: Pepti:
86/100; He & She MD:
78/100

Formulation Options: Pepti:
66/100; He & She MD:
90/100

Clinical Oversight: Pepti:
86/100; He & She MD:
85/100

Contract Flexibility: Pepti:
67/100; He & She MD:
31/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

Alternatives to Pepti Alternatives to He & She MD

More provider matchups

CoreAge Rx vs Pepti CoreAge Rx vs He & She MD

Choose a different comparison

Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.