Head-to-head · Cost-Efficiency Index
Ozari Health vs Trillium Meds
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Ozari Health
Cost-first shoppers who want legitScript-certified compounded GLP-1 from as low as $86/month.
Visit Ozari HealthTrillium Meds
Cost-first shoppers who want all-50-state compounded GLP-1 with a real month-to-month option and a cheaper 3-month prepay path.
Visit Trillium MedsThe verdict
Ozari Health and Trillium Meds tie on the Cost-Efficiency Index at 73/100, so neither wins outright on the numbers. For most shoppers we'd start with Ozari Health (ranked #70, a hair above #71) — Cost-first shoppers who want legitScript-certified compounded GLP-1 from as low as $86/month. But Trillium Meds is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Ozari Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Ozari Health | Trillium Meds |
|---|---|---|
| Cost-Efficiency Index | 73/100 | 73/100 |
| Semaglutide / mo | $86/mo (3-mo starter plan, new patients only, compounded) | $159/mo (all doses, compounded) |
| Tirzepatide / mo | $125/mo (3-mo starter plan, new patients only, compounded) | $249/mo (all doses, compounded) |
| Semaglutide / yr (modeled) | $1,032 | $1,908 |
| Tirzepatide / yr (modeled) | $1,500 | $2,988 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #70 | #71 |
Ozari Health
73/100Where the value is
- Very low entry pricing — compounded semaglutide from $86/month
- LegitScript certified and operated by a named entity (Ozari LLC)
- Board-certified physicians; meds compounded in 503A and 503B facilities
The tradeoffs
- The advertised rates are three-month starter plans for first-time GLP-1 users, billed $257 and $375 up front; month-to-month is $175 and $235
- Canceling an annual or semi-annual plan early re-prices the installments already shipped at the standard monthly rate and charges the difference
Trillium Meds
73/100Where the value is
- Discloses both a real month-to-month rate ($159/$249) and the 3-month prepay rate, rather than only advertising the lower prepay number
- LegitScript certified, all 50 states plus Puerto Rico, with a real street address published
- Syringes and alcohol wipes included; Klarna and Affirm financing available
The tradeoffs
- The lowest advertised rate ($119/mo semaglutide, ~$200/mo tirzepatide) requires a $357 or $599 upfront 3-month payment, not a standing monthly charge
- Partner pharmacy names are referenced in the FAQ structure but were not visible in the page text pulled this session — re-verify before citing a specific pharmacy
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.