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Head-to-head · Cost-Efficiency Index

Onyx Weight Loss vs Woodwork

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #402

Onyx Weight Loss

Patients located in one of Onyx's 8 served states who want a boutique, NP-led clinic bundling weight loss with hormone and peptide care.

Visit Onyx Weight Loss
VS
Grade C · #405

Woodwork

Cost-first shoppers who want grindr users or men already comfortable with the brand who want ED, GLP-1, and peptide/supplement care bundled under one telehealth account.

Visit Woodwork

The verdict

Too close to callGrade C vs C

Onyx Weight Loss and Woodwork tie on the Cost-Efficiency Index at 51/100, so neither wins outright on the numbers. For most shoppers we'd start with Onyx Weight Loss (ranked #402, a hair above #405) — Patients located in one of Onyx's 8 served states who want a boutique, NP-led clinic bundling weight loss with hormone and peptide care. But Woodwork is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Onyx Weight Loss.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
59

Price Transparency

54
30

Nationwide Access

42
24

Formulation Options

40
77

Clinical Oversight

76
83

Contract Flexibility

55
41

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecOnyx Weight LossWoodwork
Cost-Efficiency Index51/10051/100
Semaglutide / moNot disclosed$127/mo (starting dose, compounded oral)
Tirzepatide / moNot disclosed$199/mo (starting dose, compounded)
Semaglutide / yr (modeled)$1,524
Tirzepatide / yr (modeled)$2,388
Coverage8 statesCoverage not published
Oral / sublingualNoYes
Brand-name accessCompounded onlyCompounded only
Rank here#402#405

Onyx Weight Loss

51/100

Where the value is

  • Clear, specific 8-state service list published
  • Bundles weight loss with hormone replacement and peptide therapy under one clinic
  • Small team with named founders and identifiable clinical staff

The tradeoffs

  • No pricing published anywhere on the public site
  • No physician/MD medical director -- leadership is NP/RN-only
Visit Onyx Weight Loss

Full Onyx Weight Loss review →

Woodwork

51/100

Where the value is

  • Backed by an established consumer brand (Grindr LLC) with real infrastructure
  • Competitive 'from' pricing on both semaglutide ($127/mo) and tirzepatide ($199/mo)
  • Oral tablet option available for semaglutide in addition to injections

The tradeoffs

  • GLP-1 is a secondary offering -- the platform's primary identity and marketing focus is ED medication, not weight loss
  • No named medical director or clinical leadership found on any accessible page
Visit Woodwork

Full Woodwork review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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